Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12913880 | 0.93 | TSHR (0.36) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL12993045 | 0.90 | TSHR (0.36) | TSHRCYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL12609535 | 0.90 | TSHR (0.36) | TSHRCYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL12890738 | 0.89 | TSHR (0.36) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL11012846 | 0.87 | TSHR (0.43) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL12609605 | 0.85 | CYP4F2 (0.34) | TSHRCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL27366742 | 0.85 | TSHR (0.40) | TSHRCYP3A4TDP1CYP4F2CYP4A11 | |
| SCHEMBL750654 | 0.83 | TSHR (0.43) | TSHRCYP3A4TDP1CYP4F2CYP4A11 | |
| SCHEMBL10033540 | 0.82 | TSHR (0.40) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL10033545 | 0.81 | TSHR (0.39) | TSHRCYP3A4TDP1MAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168370-B2 | Photosensitive composition which included photopolymerization initiator; graft polymer binder | FUJIFILM CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |