SCHEMBL4544795

SCHEMBL4544795

COC(=O)c1ccccc1Nc1nc(Nc2ccccc2C)nc(Nc2ccccc2C(=O)OC)n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.58
ALOX15 P16050 1/20 0.58
KDM4E B2RXH2 6/20 0.54
POLB P06746 3/20 0.54
ATM Q13315 1/20 0.54
PTK2 Q05397 1/20 0.54
ALDH1A1 P00352 3/20 0.53
KMT2A Q03164 2/20 0.53
PTGS2 P35354 1/20 0.53
ALOX12 P18054 1/20 0.53
NPC1 O15118 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
HPGD P15428 1/20 0.50
AURKA O14965 1/20 0.49
RAB9A P51151 1/20 0.48
GLA P06280 1/20 0.48
HSD17B10 Q99714 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
GAA P10253 1/20 0.46
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13383866 1.00 MAPT (0.58) MAPTALOX15KDM4EPOLBATM
SCHEMBL14079360 0.91 MAPT (0.49) MAPTALOX15KDM4EPOLBATM
SCHEMBL17145917 0.89 MAPT (0.67) MAPTALOX15KDM4EPOLBATM
SCHEMBL30294456 0.89 MAPT (0.67) MAPTALOX15KDM4EPOLBATM
SCHEMBL4544804 0.88 PTK2 (0.52) MAPTALOX15KDM4EPOLBATM
SCHEMBL4544793 0.85 MAPT (0.77) MAPTALOX15KDM4EPOLBATM
SCHEMBL12605599 0.84 MAPT (0.76) MAPTALOX15KDM4EPOLBATM
SCHEMBL4544791 0.81 MAPT (0.57) MAPTALOX15KDM4EPOLBATM
SCHEMBL12109338 0.81 MAPT (0.69) MAPTALOX15KDM4EPOLBATM
SCHEMBL14079362 0.80 PTK2 (0.46) MAPTALOX15KDM4EPOLBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8203675-B2 Liquid-crystal display device having retardation films with different optical anisotropy FUJIFILM CORPORATION (JP) 2012-06-19 US disclosed
US-8178601-B2 Polymer film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-7981488-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-20100220272-A1 LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2010-09-02 US disclosed
US-7667801-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-02-23 US disclosed
US-20100020273-A1 POLYMER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2010-01-28 US disclosed
US-7651743-B2 Cellulose acylate film, manufacturing method of cellulose acylate film, optically compensatory sheet, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-26 US disclosed
US-7611760-B2 Cellulose acylate film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2009-11-03 US disclosed
US-20090251650-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2009-10-08 US disclosed
US-20090207355-A1 LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-08-20 US disclosed
US-20090066887-A1 Polymer Film, Polarizing Plate Protective Film, Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-03-12 US disclosed
US-20080226888-A1 Cellulose Acylate Film, Polarizing Plate and Liquid Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080213511-A1 Optical compensation film, process for producing optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-09-04 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080198303-A1 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed