SCHEMBL4544804

SCHEMBL4544804

COC(=O)c1ccccc1Nc1nc(Nc2ccc(C)cc2C)nc(Nc2ccccc2C(=O)OC)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 1/20 0.52
MAPT P10636 5/20 0.51
ALOX15 P16050 1/20 0.51
KDM4E B2RXH2 7/20 0.48
ALDH1A1 P00352 4/20 0.48
HPGD P15428 1/20 0.48
HSD17B10 Q99714 1/20 0.48
GLA P06280 1/20 0.48
PTGS2 P35354 1/20 0.48
POLB P06746 2/20 0.48
ATM Q13315 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
TP53 P04637 2/20 0.47
LMNA P02545 1/20 0.47
KMT2A Q03164 4/20 0.46
ALOX12 P18054 2/20 0.46
NPC1 O15118 1/20 0.45
AURKA O14965 1/20 0.45
CISD2 Q8N5K1 1/20 0.44
PRMT5 O14744 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14079362 0.92 PTK2 (0.46) PTK2MAPTALOX15KDM4EALDH1A1
SCHEMBL13383866 0.88 MAPT (0.58) PTK2MAPTALOX15KDM4EALDH1A1
SCHEMBL4544795 0.88 MAPT (0.58) PTK2MAPTALOX15KDM4EALDH1A1
SCHEMBL4544791 0.83 MAPT (0.57) PTK2MAPTALOX15KDM4EALDH1A1
SCHEMBL14079360 0.80 MAPT (0.49) PTK2MAPTALOX15KDM4EALDH1A1
SCHEMBL4544793 0.79 MAPT (0.77) PTK2MAPTALOX15KDM4EHSD17B10
SCHEMBL11564238 0.78 RAPGEF4 (0.61) MAPTALOX15KDM4EALDH1A1POLB
SCHEMBL20419769 0.77 PTGS2 (0.62) MAPTALOX15KDM4EALDH1A1HPGD
SCHEMBL22853413 0.77 MAPT (0.55) MAPTALOX15KDM4EALDH1A1HPGD
SCHEMBL30294693 0.77 MAPT (0.55) MAPTALOX15KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8203675-B2 Liquid-crystal display device having retardation films with different optical anisotropy FUJIFILM CORPORATION (JP) 2012-06-19 US disclosed
US-8178601-B2 Polymer film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-7981488-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-20100220272-A1 LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2010-09-02 US disclosed
US-7697095-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-04-13 US disclosed
US-7667801-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-02-23 US disclosed
US-20100020273-A1 POLYMER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2010-01-28 US disclosed
US-7651743-B2 Cellulose acylate film, manufacturing method of cellulose acylate film, optically compensatory sheet, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-26 US disclosed
US-7611760-B2 Cellulose acylate film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2009-11-03 US disclosed
US-20090251650-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2009-10-08 US disclosed
US-20080226888-A1 Cellulose Acylate Film, Polarizing Plate and Liquid Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080213511-A1 Optical compensation film, process for producing optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-09-04 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080198303-A1 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed