SCHEMBL4544890

SCHEMBL4544890

CCCCCc1ccc(OC(=O)C2CCC(C(=O)Oc3ccc(CCCCC)cc3)CC2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 5/20 0.61
THRA P10827 3/20 0.61
F2 P00734 1/20 0.54
HTT P42858 1/20 0.53
KMT2A Q03164 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
ALDH1A1 P00352 2/20 0.49
S1PR1 P21453 3/20 0.48
S1PR3 Q99500 3/20 0.48
S1PR4 O95977 2/20 0.48
S1PR5 Q9H228 2/20 0.48
ELANE P08246 1/20 0.48
RARB P10826 1/20 0.45
ESR1 P03372 2/20 0.45
ADRA2A P08913 2/20 0.45
ADORA3 P0DMS8 2/20 0.45
TACR2 P21452 2/20 0.45
SLC6A2 P23975 2/20 0.45
SLC6A4 P31645 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7950224 1.00 THRB (0.61) THRBTHRAF2HTTKMT2A
SCHEMBL2610152 0.98 THRB (0.63) THRBTHRAF2HTTKMT2A
SCHEMBL4544911 0.98 THRB (0.63) THRBTHRAF2HTTKMT2A
SCHEMBL19077966 0.98 THRB (0.59) THRBTHRAF2HTTKMT2A
SCHEMBL4544927 0.98 THRB (0.63) THRBTHRAF2HTTKMT2A
SCHEMBL4544888 0.98 THRB (0.63) THRBTHRAF2HTTKMT2A
SCHEMBL4544897 0.96 THRB (0.60) THRBTHRAF2HTTKMT2A
SCHEMBL4544892 0.95 F2 (0.56) THRBTHRAF2HTTKMT2A
SCHEMBL7941967 0.95 F2 (0.56) THRBTHRAF2HTTKMT2A
SCHEMBL13198329 0.94 THRB (0.59) THRBTHRAF2HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE37270-E1 EXCELLENT ELECTRO-OPTIC STEEPNESS AND VIEWING ANGLE COMBINED WITH BIREFRINGENCE FOR USE IN STANDARD DISPLAY CELLS; MIXTURE OF 4-CYANO-3-FLUOROPHENYL BENZOATES, BENZONITRILES, ALKYLPHENYL ESTERS OF CYCLOHEXANE OR PHENYLCARBOXYLIC ACIDS MERCK PATENT GESELLSCHAFT (DE) 2001-07-10 US claimed
EP-0285617-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1991-12-27 EP claimed
US-4886621-A ACCEPTABLE COMBINATION OF THRESHOLD STEEPNESS, VIEWING ANGLE AND TEMPERATURE DEPENDENCE AT LOW THRESHOLD VOLTAGE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-12-12 US claimed
US-9581728-B2 Retardation film, polarizing plate and liquid crystal display Konica Minolta, Inc. (JP) 2017-02-28 US disclosed
US-9223070-B2 Optical film, polarizing plate equipped with the optical film, process for manufacture of the polarizing plate, and liquid crystal display device Konica Minolta, Inc. (JP) 2015-12-29 US disclosed
US-20150323703-A1 RETARDATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-11-12 US disclosed
US-20130293812-A1 OPTICAL FILM, POLARIZING PLATE EQUIPPED WITH THE OPTICAL FILM, PROCESS FOR MANUFACTURE OF THE POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2013-11-07 US disclosed
US-8502937-B2 Protective film for polarizers FUJIFILM CORPORATION (JP) 2013-08-06 US disclosed
US-8477274-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-8425991-B2 Cellulose acylate film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
US-8350995-B2 Optical film, production method of optical film, optically-compensatory film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-01-08 US disclosed
US-20070134446-A1 Retardation film, method for producing the same, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. 2007-06-14 US disclosed
US-20070097302-A1 RETARDATION FILM, POLARIZING PLATE AND VERTICAL ALIGNMENT MODE LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2007-05-03 US disclosed
US-20070081115-A1 Polarizing plate and image display device using the same FUJIFILM CORPORATION (JP) 2007-04-12 US disclosed
US-20070019133-A1 Polarizing plate and liquid crystal display device KONICA MINOLTA OPTO, INC. (JP) 2007-01-25 US disclosed
US-RE37270-E1 EXCELLENT ELECTRO-OPTIC STEEPNESS AND VIEWING ANGLE COMBINED WITH BIREFRINGENCE FOR USE IN STANDARD DISPLAY CELLS; MIXTURE OF 4-CYANO-3-FLUOROPHENYL BENZOATES, BENZONITRILES, ALKYLPHENYL ESTERS OF CYCLOHEXANE OR PHENYLCARBOXYLIC ACIDS MERCK PATENT GESELLSCHAFT (DE) 2001-07-10 US disclosed
EP-0285617-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1991-12-27 EP disclosed
US-4886621-A ACCEPTABLE COMBINATION OF THRESHOLD STEEPNESS, VIEWING ANGLE AND TEMPERATURE DEPENDENCE AT LOW THRESHOLD VOLTAGE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-12-12 US disclosed
EP-0285617-A1 LIQUID CRYSTAL PHASE. MERCK PATENT GMBH (DE) 1988-10-12 EP disclosed
WO-1988002018-A1 LIQUID CRYSTAL PHASE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-03-24 WO disclosed