Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 19/20 | 0.78 |
| ▸ | PDE3B | Q13370 | 14/20 | 0.78 |
| ▸ | PDE3A | Q14432 | 14/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4545440 | 0.90 | PDE10A (0.77) | PDE10APDE3BPDE3A | |
| SCHEMBL4545884 | 0.90 | PDE10A (0.77) | PDE10APDE3BPDE3A | |
| SCHEMBL30123166 | 0.88 | PDE10A (1.00) | PDE10APDE3BPDE3A | |
| SCHEMBL2451079 | 0.88 | PDE10A (1.00) | PDE10APDE3BPDE3A | |
| SCHEMBL2725365 | 0.88 | PDE10A (1.00) | PDE10APDE3BPDE3A | |
| SCHEMBL4404999 | 0.88 | PDE10A (1.00) | PDE10APDE3BPDE3A | |
| SCHEMBL2729925 | 0.87 | PDE10A (0.73) | PDE10APDE3BPDE3A | |
| SCHEMBL10063737 | 0.87 | PDE10A (0.73) | PDE10APDE3BPDE3A | |
| SCHEMBL2731771 | 0.87 | PDE10A (0.73) | PDE10APDE3BPDE3A | |
| SCHEMBL2731328 | 0.87 | PDE10A (0.73) | PDE10APDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012052556-A1 | NOVEL HALOALKOXYQUINAZOLINES, AND PREPARATION AND USE THEREOF | UNIVERSITÄT LEIPZIG (DE) | 2012-04-26 | — | — | WO | disclosed |