SCHEMBL454602

SCHEMBL454602

CCCCCCCC/C=C\CCCCCCCC(C)OC(=O)c1ccccc1C(=O)O

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.85
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
TSHR P16473 2/20 0.45
LMNA P02545 1/20 0.45
SOAT2 O75908 1/20 0.44
SOAT1 P35610 1/20 0.44
KDM4E B2RXH2 2/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
FAAH O00519 2/20 0.43
EPHX2 P34913 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
MMP2 P08253 2/20 0.42
F7 P08709 2/20 0.42
F3 P13726 2/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL454601 0.95 ALDH1A1 (0.76) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL31650681 0.94 ALDH1A1 (0.74) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL6400267 0.92 ALDH1A1 (1.00) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL6405741 0.92 ALDH1A1 (1.00) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL3782139 0.92 ALDH1A1 (1.00) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL1417173 0.92 ALDH1A1 (1.00) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL6400038 0.92 ALDH1A1 (1.00) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL6400496 0.92 ALDH1A1 (1.00) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL17258282 0.92 ALDH1A1 (1.00) ALDH1A1PRSS1PRSS2PRSS3TSHR
SCHEMBL6400394 0.92 ALDH1A1 (1.00) ALDH1A1PRSS1PRSS2PRSS3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2423753-B1 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same RICOH CO LTD (JP) 2016-10-19 EP disclosed
EP-1199613-B1 Method for removing deposit from image substrate and image formation apparatus using the method RICOH CO LTD (JP) 2015-12-09 EP disclosed
EP-1484647-B1 Photoreceptor, image forming method and image forming apparatus using the photoreceptor, process cartridge using the photoceptor and coating liquid for the photoceptor RICOH CO LTD (JP) 2015-07-29 EP disclosed
US-9040215-B2 Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-05-26 US disclosed
US-9031491-B2 Image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2015-05-12 US disclosed
US-8889324-B2 Image bearing member, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2014-11-18 US disclosed
US-8831467-B2 Image-forming apparatus RICOH COMPANY, LTD. (JP) 2014-09-09 US disclosed
US-8809543-B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus RICOH COMPANY, LTD. (JP) 2014-08-19 US disclosed
EP-2535774-B1 Image bearing drum, image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2014-07-30 EP disclosed
US-20130251401-A1 IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-09-26 US disclosed
EP-0976681-A2 Novel fine particulate synthetic chalcoalumite compounds, process for their production, and heat insulator and agricultural film containing the fine particulate synthetic chalcoalumite compounds KYOWA CHEMICAL INDUSTRY CO., LTD. (JP) 2000-02-02 EP disclosed
US-5824759-A POLYPROPYLENE HOMOPOLYMERS OR COPOLYMERS WITH PEROXIDES SHOWA DENKO K.K. (JP) 1998-10-20 US disclosed
EP-0434067-B1 Polymer compositions KURARAY CO (JP) 1997-09-03 EP disclosed
EP-0752447-A1 PROPYLENE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF SHOWA DENKO KABUSHIKI KAISHA (JP) 1997-01-08 EP disclosed
US-5321078-A Polyester and grft polymer blend; improved impact resistance and chemnical resistance HITACHI CHEMICAL CO., LTD. (JP) 1994-06-14 US disclosed
US-5122561-A Dihydrofuran polymer with or without plasticizer, phenolic compound; decompose in environment KURARAY CO., LTD. (JP) 1992-06-16 US disclosed
EP-0434067-A2 Polymer compositions KURARAY CO., LTD. (JP) 1991-06-26 EP disclosed
US-4803260-A AGGREGATION WITH A WATER INSOLUBLE LIQUID, SEPARATION, AND DEHYDRATION NIPPON ZEON CO., LTD. (JP) 1989-02-07 US disclosed
US-4721773-A MIXING, AGGREGATION NIPPON ZEON CO., LTD. (JP) 1988-01-26 US disclosed
US-4424834-A PVC, PLASTICIZER, THERMOPLASTIC ELASTOMERS KYORAKU CO., LTD. (JP) 1984-01-10 US disclosed