AKR1D1

Aldo-keto reductase family 1 member D1 · P51857 · AKR1D1 on Sugi Atlas →

0 patent compounds predicted against AKR1D1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to AKR1D1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Role of 5-alpha Reductase in Mediating Testosterone Actions PHASE4COMPLETED
The Effect of Calcium and Vitamin D Supplements on Metabolic and Hormonal Disturbances in Polycystic Ovary Syndrome Patients PHASE3COMPLETED
Vitamin D and SGLT-2 Inhibitor in CPAP-naive Obstructive Sleep Apnea PHASE3COMPLETED
Androgen Ablation Therapy With or Without Chemotherapy in Treating Patients With Metastatic Prostate Cancer PHASE3COMPLETED
Toxicity and Efficacy Evaluation of Topical Minoxidil in Acne Vulgaris PHASE1/PHASE2UNKNOWN
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
AMG 386 and Abiraterone for Advanced Prostate Cancer PHASE2COMPLETED
A Phase Ib/II Clinical Study of AK127 in Combination With AK112 in Patients With Advanced Solid Tumors PHASE1/PHASE2ACTIVE_NOT_RECRUITING
Biomarkers in Bone Marrow and Blood Samples From Patients With Prostate Cancer Treated With Ketoconazole nanWITHDRAWN
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages nanCOMPLETED
5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy nanRECRUITING
Tissue Predictors of Abiraterone Benefit nanCOMPLETED
Adrenoleukodystrophy National Registry Study nanRECRUITING
ALDH2 Genetic Testing in East Asian Community nanNOT_YET_RECRUITING
Final Height in Patients With CAH nanUNKNOWN
Mutation Analysis of 17βhydroxysteroid Dehydrogenase 3 Deficiency nanUNKNOWN
Genetic, Dietary and Environmental Influences on Vitamin D Metabolism nanCOMPLETED
Replacement of Vitamin D in Patients With Active Tuberculosis nanCOMPLETED
Gene Polymorphisms Influencing Steroid Synthesis and Action nanWITHDRAWN
The RolE oF Androgen Excess in MUscle Energy MetaboLism in Women With PolyCystic Ovary Syndrome (REFUEL PCOS) Study 2 nanUNKNOWN
A Study of Genetic Influence on LDL Hyper-responsiveness in Patients Following a Ketogenic Diet nanRECRUITING
EndoNAFLD: Relationship Between Fatty Liver Disease and Cardiovascular Diseases nanCOMPLETED
Influence of WNT4 VEZT FSHB and SIRT1 SNPs in Endometriosis: a Case Control Study of the Sardinian Population nanUNKNOWN
Biomarkers in the Etiology of Idiopathic Intracranial Hypertension nanUNKNOWN
Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside nanUNKNOWN
Pattern of Gene Expression in Adipose Tissue From Patients With Cushing Syndrome nanCOMPLETED
Exercise Capacity, Physical Fitness, and Physical Activity Levels in Children With CAH nanCOMPLETED
Drug Metabolizing Enzyme and Transporter Function in Chronic Kidney Disease nanCOMPLETED
Environmental and Biological Monitoring Pilot Study for Polycyclic Aromatic Hydrocarbons in Linxian, China nanCOMPLETED
Evaluation of Hydroxymethylbutyrate Supplementation in Lung Transplant Candidates Receiving Pulmonary Rehabilitation nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a AKR1D1 binder may also engage these)

ProteinNameSimilarity
Q8VCX1 1.000 Q8VCX1 →
Q9TV64 1.000 Q9TV64 →
P31210 1.000 P31210 →
P17264 0.999 P17264 →
Q28FD1 0.997 Q28FD1 →
P80276 0.997 P80276 →
P21300 0.996 P21300 →
P82125 0.996 P82125 →
P45376 0.996 P45376 →
P02532 0.996 P02532 →
P16116 0.994 P16116 →
P07943 0.993 P07943 →
O08782 0.992 O08782 →
AKR1A1 Aldo-keto reductase family 1 member A1 0.992 landscape →
M9PF61 0.992 M9PF61 →
C9JRZ8 0.992 C9JRZ8 →
Q9DCT1 0.991 Q9DCT1 →
Q5U1Y4 0.991 Q5U1Y4 →
O70473 0.991 O70473 →
Q5RJP0 0.991 Q5RJP0 →
Q6GMC7 0.991 Q6GMC7 →
AKR1B1 Aldo-keto reductase family 1 member B1 0.990 landscape →
AKR1B10 Aldo-keto reductase family 1 member B10 0.990 landscape →
P15122 0.990 P15122 →
Q3ZCJ2 0.988 Q3ZCJ2 →
Q5ZK84 0.988 Q5ZK84 →
Q9SQ64 0.988 Q9SQ64 →
Q6AZW2 0.987 Q6AZW2 →
Q0PGJ6 0.987 Q0PGJ6 →
Q4R802 0.987 Q4R802 →