SCHEMBL4546845

SCHEMBL4546845

Cc1cc(-c2cccc(-c3cccc(-n4c5ccccc5c5ccccc54)c3)c2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.47
KDM4E B2RXH2 2/20 0.47
ATM Q13315 1/20 0.47
GAA P10253 3/20 0.38
RXFP1 Q9HBX9 1/20 0.38
ALDH1A1 P00352 4/20 0.36
PKM P14618 1/20 0.35
LMNA P02545 2/20 0.34
MAPT P10636 2/20 0.34
HTT P42858 2/20 0.34
KMT2A Q03164 3/20 0.34
IL1R1 P14778 1/20 0.34
OPRD1 P41143 1/20 0.34
MEN1 O00255 2/20 0.33
PMM2 O15305 1/20 0.33
MPI P34949 1/20 0.33
PHOSPHO1 Q8TCT1 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
FTO Q9C0B1 1/20 0.33
GRM5 P41594 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4546839 0.98 L3MBTL1 (0.48) L3MBTL1KDM4EATMGAARXFP1
SCHEMBL12346089 0.97 L3MBTL1 (0.50) L3MBTL1KDM4EATMGAARXFP1
SCHEMBL20418770 0.94 L3MBTL1 (0.52) L3MBTL1KDM4EATMGAARXFP1
SCHEMBL4546848 0.94 KDM4E (0.50) L3MBTL1KDM4EATMGAARXFP1
SCHEMBL25014416 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMRXFP1ALDH1A1
SCHEMBL4546835 0.90 L3MBTL1 (0.50) L3MBTL1KDM4EATMGAARXFP1
SCHEMBL4546817 0.90 L3MBTL1 (0.50) L3MBTL1KDM4EATMGAARXFP1
SCHEMBL12258329 0.90 L3MBTL1 (0.57) L3MBTL1KDM4EATMGAAALDH1A1
SCHEMBL25693022 0.90 KDM4E (0.52) L3MBTL1KDM4EATMRXFP1ALDH1A1
SCHEMBL15435807 0.90 KDM4E (0.43) L3MBTL1KDM4EATMGAARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178215-B2 Organic compound containing at least two carbazolyl-substituted phenyl structures; charge-transporting material and organic el element containing the compound PIONEER CORPORATION (JP) 2012-05-15 US disclosed
US-8178215-B2 Organic compound containing at least two carbazolyl-substituted phenyl structures; charge-transporting material and organic el element containing the compound PIONEER CORPORATION (JP) 2012-05-15 US disclosed
US-20090236973-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT PIONEER CORPORATION (JO) 2009-09-24 US disclosed
US-20090236973-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT PIONEER CORPORATION (JO) 2009-09-24 US disclosed
EP-1820801-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT Pioneer Corporation (JP) 2007-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090236973-A1 ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLCO4C1, SLCO2A1, SLCO2B1 L3MBTL1 702/4885KDM4E 2187/4885ATM 4266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.