Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4547673 | 0.80 | MMP12 (0.37) | — | |
| SCHEMBL4547663 | 0.78 | ANPEP (0.44) | POLB | |
| SCHEMBL4547662 | 0.77 | POLB (0.31) | POLB | |
| SCHEMBL13629737 | 0.77 | TSHR (0.32) | SMN1; SMN2 | |
| SCHEMBL4547666 | 0.77 | CYP4A11 (0.43) | ALDH1A1 | |
| SCHEMBL12249323 | 0.71 | ACE (0.51) | ACEALDH1A1SMN1; SMN2 | |
| SCHEMBL7266830 | 0.71 | ACE (0.51) | ACEALDH1A1SMN1; SMN2 | |
| SCHEMBL10327471 | 0.69 | CYP2A6 (0.41) | ACEALDH1A1 | |
| SCHEMBL4547658 | 0.67 | CYP1A2 (0.39) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL7266310 | 0.66 | ACE (0.47) | POLBACEALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173704-B2 | Difluorophenol derivatives and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20090291993-A1 | Difluorophenol Derivatives and Their Use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291993-A1 | Difluorophenol Derivatives and Their Use | TPMT, FABP3, DPP4 | POLB 1590/4885ACE 213/4885ALDH1A1 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.