SCHEMBL4547689

SCHEMBL4547689

CN1C(C)(C)CC(OC(=O)CCCCCCCC(=O)OC2CC(C)(C)NC(C)(C)C2)CC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.41
GAA P10253 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
EPHX2 P34913 3/20 0.32
TP53 P04637 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
NPC1L1 Q9UHC9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12140917 1.00 NAAA (0.41) NAAAGAASMN1; SMN2MEN1KMT2A
SCHEMBL22161944 0.99 GAA (0.41) NAAAGAASMN1; SMN2MEN1KMT2A
SCHEMBL28066973 0.95 GAA (0.40) NAAAGAASMN1; SMN2MEN1KMT2A
SCHEMBL27165052 0.95 NAAA (0.50) NAAAGAASMN1; SMN2
SCHEMBL15961515 0.93 GAA (0.43) NAAAGAASMN1; SMN2MEN1KMT2A
SCHEMBL12244967 0.91 NAAA (0.47) NAAAGAASMN1; SMN2MEN1KMT2A
SCHEMBL28367479 0.91 NAAA (0.47) NAAAGAASMN1; SMN2MEN1KMT2A
SCHEMBL28840529 0.91 NAAA (0.47) NAAAGAASMN1; SMN2MEN1KMT2A
SCHEMBL21127012 0.91 NAAA (0.47) NAAAGAASMN1; SMN2MEN1KMT2A
SCHEMBL13226047 0.91 NAAA (0.47) NAAAGAASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815987-B2 Polypropylene mineral compound with reduced volatiles BOREALIS AG (AT) 2014-08-26 US disclosed
US-20120123033-A1 POLYPROPYLENE MINERAL COMPOUND WITH REDUCED VOLATILES BOREALIS AG (AT) 2012-05-17 US disclosed
US-20120115995-A1 AUTOMOTIVE INTERIOR ARTICLE WITH REDUCED SMELL BOREALIS AG (AT) 2012-05-10 US disclosed
US-20100286310-A1 LOW-STICKY ADDITIVE PACKAGE FOR AUTOMOTIVE INTERIOR APPLICATIONS BOREALIS AG (AT) 2010-11-11 US disclosed