Pomiferin A

Pomiferin A

SCHEMBL4549111

CC(C)c1ccc2c(c1)CCC1C(C)(CO)CCCC21C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KARS1 Q15046 3/20 1.00
CYP3A4 P08684 4/20 0.79
MEN1 O00255 3/20 0.79
KMT2A Q03164 3/20 0.79
TSHR P16473 2/20 0.79
CYP2D6 P10635 2/20 0.79
CYP2C19 P33261 2/20 0.79
PDK1 Q15118 1/20 0.79
PDK2 Q15119 1/20 0.79
PDK3 Q15120 1/20 0.79
PDK4 Q16654 1/20 0.79
CYP2C9 P11712 1/20 0.79
MAPK1 P28482 2/20 0.77
TP53 P04637 1/20 0.77
MAPT P10636 1/20 0.77
ALOX15 P16050 1/20 0.77
RXRA P19793 1/20 0.70
CCNE1 P24864 1/20 0.70
CDK2 P24941 1/20 0.70
RXRB P28702 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pomiferin A SCHEMBL13039025 1.00 KARS1 (1.00) KARS1CYP3A4MEN1KMT2ATSHR
Pomiferin A SCHEMBL30087017 1.00 KARS1 (1.00) KARS1CYP3A4MEN1KMT2ATSHR
Pomiferin A SCHEMBL1210740 1.00 KARS1 (1.00) KARS1CYP3A4MEN1KMT2ATSHR
Pomiferin A SCHEMBL2546195 1.00 KARS1 (1.00) KARS1CYP3A4MEN1KMT2ATSHR
Pomiferin A SCHEMBL2728630 1.00 KARS1 (1.00) KARS1CYP3A4MEN1KMT2ATSHR
SCHEMBL20866442 0.91 KARS1 (0.83) KARS1CYP3A4MEN1KMT2ATSHR
SCHEMBL16298228 0.89 CYP3A4 (0.80) KARS1CYP3A4MEN1KMT2ATSHR
SCHEMBL6018371 0.88 CYP3A4 (0.79) KARS1CYP3A4MEN1KMT2ATSHR
SCHEMBL27863 0.88 CYP3A4 (1.00) KARS1CYP3A4MEN1KMT2ATSHR
SCHEMBL9108470 0.88 CYP3A4 (1.00) KARS1CYP3A4MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962230-B2 Electrostatic-image developing toner, electrostatic image developer, toner cartridge, process cartridge, image-forming apparatus, and method for forming image FUJI XEROX CO., LTD. (JP) 2015-02-24 US disclosed
US-20130022907-A1 POLYMER DERIVED FROM DEHYDROABIETIC ACID AND USES THEREOF FUJIFILM CORPORATION (JP) 2013-01-24 US disclosed
US-20130022907-A1 POLYMER DERIVED FROM DEHYDROABIETIC ACID AND USES THEREOF FUJIFILM CORPORATION (JP) 2013-01-24 US disclosed
US-20120114715-A1 USE OF LARCH WOOD FOR TREATING INFLAMMATION Aristotle University of Thessalokiki (GR) 2012-05-10 US disclosed
US-20120114715-A1 USE OF LARCH WOOD FOR TREATING INFLAMMATION Aristotle University of Thessalokiki (GR) 2012-05-10 US disclosed
US-20110045083-A1 USE LARCH WOOD FOR TREATING INFLAMMATION ARISTOTLE UNIVERSITY OF THESSALONIKI (GR) 2011-02-24 US disclosed
US-20110045083-A1 USE LARCH WOOD FOR TREATING INFLAMMATION ARISTOTLE UNIVERSITY OF THESSALONIKI (GR) 2011-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120114715-A1 USE OF LARCH WOOD FOR TREATING INFLAMMATION LARP1, LARP7, TNF KARS1 575/4885CYP3A4 1649/4885MEN1 4744/4885
US-20110045083-A1 USE LARCH WOOD FOR TREATING INFLAMMATION LARP1, LARP7, TNF KARS1 432/4885CYP3A4 1516/4885MEN1 4653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.