Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258245 | 1.00 | BACE1 (0.54) | BACE1CTSD | |
| SCHEMBL16480325 | 1.00 | BACE1 (0.54) | BACE1CTSD | |
| SCHEMBL8436759 | 0.89 | BACE1 (0.40) | BACE1 | |
| SCHEMBL12916850 | 0.81 | BACE1 (0.44) | BACE1CTSD | |
| SCHEMBL8247675 | 0.81 | BACE1 (0.44) | BACE1CTSD | |
| SCHEMBL12172351 | 0.80 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL4549145 | 0.80 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL2948975 | 0.78 | HCAR3 (0.32) | — | |
| SCHEMBL2948973 | 0.78 | HCAR3 (0.32) | — | |
| SCHEMBL2948978 | 0.78 | HCAR3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168641-B2 | Aspartyl protease inhibitors | SCHERING CORPORATION (US) | 2012-05-01 | — | — | US | disclosed |