SCHEMBL454916

SCHEMBL454916

CCCCCc1ccnnn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.47
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MIF P14174 1/20 0.38
CYP19A1 P11511 7/20 0.37
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
HSPD1 P10809 1/20 0.34
ADRB3 P13945 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29886625 0.98 KCNH2 (0.50) KCNH2TDP1L3MBTL1MIFCYP19A1
SCHEMBL2708608 0.98 KCNH2 (0.50) KCNH2TDP1L3MBTL1MIFCYP19A1
SCHEMBL28254740 0.98 KCNH2 (0.50) KCNH2TDP1L3MBTL1MIFCYP19A1
SCHEMBL29737342 0.98 KCNH2 (0.50) KCNH2TDP1L3MBTL1MIFCYP19A1
SCHEMBL28091636 0.98 KCNH2 (0.50) KCNH2TDP1L3MBTL1MIFCYP19A1
Benzene SCHEMBL29097018 0.96 KCNH2 (0.48) KCNH2TDP1L3MBTL1MIFCYP19A1
SCHEMBL8860594 0.94 KCNH2 (0.39) KCNH2TDP1L3MBTL1MIFCYP19A1
Phthalazine SCHEMBL27723551 0.87 KCNH2 (0.45) KCNH2TDP1L3MBTL1CYP19A1GPR84
SCHEMBL8766235 0.85
Carbazole SCHEMBL29233173 0.83 GABRP (0.53) KCNH2KDM4EALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 541 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199709-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC (US) 2024-06-20 US claimed
US-11905315-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2024-02-20 US claimed
CN-116947676-A Synthesis method of alpha-hydroxyamide or 3, 3-disubstituted oxindole compound 新疆大学 2023-10-27 CN claimed
CN-116375600-A Aryl triazene compound, synthesis method thereof and application thereof in preparation of antitumor drugs 广州药本君安医药科技股份有限公司 2023-07-04 CN claimed
CN-113980044-A Preparation method of Ir-O-P type catalyst diboronic acid/ester compound 西安交通大学 2022-01-28 CN claimed
CN-113582936-A Synthesis method of palladium-catalyzed N-aryl benzotriazole derivative 长沙理工大学 2021-11-02 CN claimed
US-20210179672-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA GENISYS CREDIT UNION 2021-06-17 US claimed
EP-3211056-B1 COMPOUNDS FOR USE IN OPTO-ELECTRICAL DEVICES CDT OXFORD LTD (GB) 2020-07-22 EP claimed
CN-107311949-B Sulfonamide-substituted aryl triazine compound and preparation method and application thereof 浙江工业大学 2020-04-24 CN claimed
EP-3211056-A1 COMPOUNDS FOR USE IN OPTO-ELECTRICAL DEVICES CDT Oxford Limited (GB) 2017-08-30 EP claimed
EP-1490014-A2 PHOTOSENSITIVE ADHESIVE COMPOSITION Produits Dentaires PIERRE ROLLAND (FR) 2004-12-29 EP claimed
WO-2003082218-A2 PHOTOSENSITIVE ADHESIVE COMPOSITION PRODUITS DENTAIRES PIERRE ROLLAND (FR) 2003-10-09 WO claimed
EP-0937716-B1 Process for the preparation of phenyldichloro-1,3,5-triazines CIBA SC HOLDING AG (CH) 2003-04-09 EP claimed
WO-2001034668-A1 ULTRAVIOLET ABSORBING ELECTRICALLY CONDUCTIVE ANISOTROPIC ADHESIVE MOTOROLA, INC. (US) 2001-05-17 WO claimed
US-6057444-A REACTION OF ALDEHYDE WITH BIURET IN HYDROCHLORIC ACID WITH METHYLSULFONIC ACID, OXIDATION AND CHLORINATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-05-02 US claimed
US-5760228-A FOR PLASTICS; SYNERGISTIC MIXTURES CYTEC TECHNOLOGY CORP. (US) 1998-06-02 US claimed
US-5714530-A POLYMER STABILIZATION CYTEC TECHNOLOGY CORP. (US) 1998-02-03 US claimed
EP-0483488-B1 Synergistic ultraviolet absorber compositions containing hydroxy aryl triazines and tetraalkyl piperidines CYTEC TECH CORP (US) 1997-03-12 EP claimed
US-5461151-A Stabilizer for a synthetic resin or polymeric coatings, plastics; radiation resistance CYTEC TECHNOLOGY CORPORATION (US) 1995-10-24 US claimed
EP-0483488-A1 Synergistic ultraviolet absorber compositions containing hydroxy aryl triazines and tetraalkyl piperidines CYTEC TECHNOLOGY CORP. (US) 1992-05-06 EP claimed