SCHEMBL4549357

SCHEMBL4549357

c1ccc(-c2ccccc2-c2ccc3cc(-c4ccc(-c5cccc6c5sc5ccccc56)cc4)c4ccccc4c3c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.57
PRKDC P78527 5/20 0.40
PARP14 Q460N5 1/20 0.39
TNKS O95271 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38
F9 P00740 1/20 0.38
LIMK1 P53667 3/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
MPI P34949 1/20 0.36
KMT2A Q03164 1/20 0.36
S1PR4 O95977 3/20 0.35
S1PR5 Q9H228 3/20 0.35
SLC9A1 P19634 1/20 0.34
GPR3 P46089 1/20 0.34
PIK3CD O00329 2/20 0.34
PIK3CB P42338 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549351 0.95 ALOX5 (0.53) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL4549356 0.95 ALOX5 (0.53) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL4549358 0.93 ALOX5 (0.52) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL4549354 0.91 ALOX5 (0.56) ALOX5PRKDCPARP14F9MAPT
SCHEMBL21304322 0.90 ALOX5 (0.47) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL22889012 0.88 ALOX5 (0.45) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL4549355 0.88 ALOX5 (0.52) ALOX5PRKDCPARP14MAPTS1PR4
SCHEMBL17268973 0.88 ALOX5 (0.58) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL25118711 0.87 ALOX5 (0.64) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL896331 0.87 ALOX5 (0.60) ALOX5PRKDCPARP14TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885PRKDC 4132/4885PARP14 1234/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885PRKDC 4132/4885PARP14 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.