SCHEMBL4549360

SCHEMBL4549360

c1ccc2cc(-c3ccc(-c4ccc5cc(-c6ccc(-c7cccc8c7sc7ccccc78)cc6)c6ccccc6c5c4)cc3)ccc2c1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.51
S1PR5 Q9H228 11/20 0.38
S1PR4 O95977 8/20 0.38
PARP14 Q460N5 1/20 0.37
PRKDC P78527 2/20 0.37
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
GPR84 Q9NQS5 1/20 0.34
GSTP1 P09211 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549355 0.99 ALOX5 (0.52) ALOX5S1PR5S1PR4PARP14PRKDC
SCHEMBL4549359 0.92 ALOX5 (0.51) ALOX5S1PR5S1PR4PARP14PRKDC
SCHEMBL4549356 0.92 ALOX5 (0.53) ALOX5PARP14PRKDCHSD17B1HSD17B2
SCHEMBL4549351 0.92 ALOX5 (0.53) ALOX5PARP14PRKDCHSD17B1HSD17B2
SCHEMBL4549358 0.91 ALOX5 (0.52) ALOX5PARP14PRKDCHSD17B1HSD17B2
SCHEMBL25118634 0.90 ALOX5 (0.53) ALOX5S1PR5S1PR4PARP14PRKDC
SCHEMBL15893256 0.90 ALOX5 (0.57) ALOX5S1PR5S1PR4PARP14PRKDC
SCHEMBL25118710 0.89 ALOX5 (0.56) ALOX5S1PR5S1PR4PARP14PRKDC
SCHEMBL23448787 0.89 ALOX5 (0.46) ALOX5S1PR5S1PR4PARP14PRKDC
SCHEMBL4549279 0.89 ALOX5 (0.58) ALOX5PARP14PRKDCGPR84CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885S1PR5 4520/4885S1PR4 4621/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885S1PR5 4520/4885S1PR4 4621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.