SCHEMBL4549366

SCHEMBL4549366

c1ccc2c(c1)cc(-c1ccc(-c3cccc4c3oc3ccccc34)cc1)c1ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.60
GGPS1 O95749 1/20 0.44
PRKDC P78527 5/20 0.44
ALDH1A1 P00352 5/20 0.42
HPGD P15428 4/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
CASP1 P29466 1/20 0.42
HIF1A Q16665 1/20 0.42
PTGES2 Q9H7Z7 1/20 0.41
CYP11B1 P15538 1/20 0.41
PIK3CD O00329 1/20 0.40
PIK3CB P42338 1/20 0.40
ATM Q13315 1/20 0.39
RAB9A P51151 3/20 0.38
KDM4E B2RXH2 3/20 0.38
AHR P35869 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549374 0.98 ALOX5 (0.58) ALOX5GGPS1PRKDCALDH1A1HPGD
SCHEMBL15195386 0.94 ALOX5 (0.55) ALOX5GGPS1PRKDCALDH1A1HPGD
SCHEMBL4549380 0.94 ALOX5 (0.54) ALOX5GGPS1PRKDCALDH1A1HPGD
SCHEMBL4549373 0.93 ALOX5 (0.57) ALOX5GGPS1PRKDCALDH1A1HPGD
SCHEMBL4549372 0.92 ALOX5 (0.58) ALOX5GGPS1PRKDCALDH1A1HPGD
SCHEMBL23471651 0.92 ALOX5 (0.52) ALOX5GGPS1PRKDCALDH1A1HPGD
SCHEMBL4549371 0.91 ALOX5 (0.58) ALOX5GGPS1PRKDCALDH1A1HPGD
SCHEMBL4549378 0.91 ALOX5 (0.57) ALOX5GGPS1PRKDCALDH1A1HPGD
SCHEMBL27340090 0.91 ALOX5 (0.51) ALOX5GGPS1PRKDCALDH1A1HPGD
SCHEMBL21563829 0.90 ALOX5 (0.63) ALOX5GGPS1PRKDCALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210050542-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-18 US disclosed
WO-2020127165-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-06-25 WO disclosed
EP-3044286-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2018-01-31 EP disclosed
US-20160226001-A1 Organic Electroluminescent Device MERCK PATENT GMBH (DE) 2016-08-04 US disclosed
US-20160226001-A1 Organic Electroluminescent Device MERCK PATENT GMBH (DE) 2016-08-04 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
WO-2015036080-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-03-19 WO disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885GGPS1 1183/4885PRKDC 4132/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885GGPS1 1183/4885PRKDC 4132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.