Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.53 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.52 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1143538 | 0.98 | CYP1A2 (0.53) | CYP1A2HSP90AA1HSP90AB1SLC40A1NFKBIA | |
| Bromide SCHEMBL27612053 | 0.97 | CYP1A2 (0.52) | CYP1A2HSP90AA1HSP90AB1SLC40A1NFKBIA | |
| 1-Hexanol SCHEMBL3915452 | 0.84 | IDO1 (0.51) | CYP1A2HSP90AA1HSP90AB1SLC40A1NFKBIA | |
| SCHEMBL8439027 | 0.83 | SLC40A1 (0.52) | CYP1A2HSP90AA1HSP90AB1SLC40A1KMT2A | |
| SCHEMBL2473645 | 0.83 | KDM4E (0.45) | CYP1A2HSP90AA1HSP90AB1SLC40A1NFKBIA | |
| SCHEMBL1556194 | 0.81 | CYP1A2 (0.52) | CYP1A2HSP90AA1HSP90AB1SLC40A1KMT2A | |
| SCHEMBL29828916 | 0.81 | CYP1A2 (0.52) | CYP1A2HSP90AA1HSP90AB1SLC40A1KMT2A | |
| SCHEMBL13219481 | 0.81 | CYP1A2 (0.52) | CYP1A2HSP90AA1HSP90AB1SLC40A1KMT2A | |
| SCHEMBL4810431 | 0.81 | CYP1A2 (0.52) | CYP1A2HSP90AA1HSP90AB1SLC40A1KMT2A | |
| SCHEMBL3563100 | 0.79 | KMT2A (0.55) | CYP1A2HSP90AA1HSP90AB1SLC40A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 871 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105337-B | Quinoline triarylamine and preparation method thereof | 湖南大学 | 2022-12-23 | — | — | CN | claimed |
| CN-111217747-B | Preparation method of pamaquine | 济南韶远医药技术有限公司 | 2022-02-22 | — | — | CN | claimed |
| CN-112151853-B | Battery pole piece with melting recombination characteristic and lithium ion battery comprising same | 浙江锋锂新能源科技有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-113248431-A | Preparation method of primaquine phosphate | 重庆医药高等专科学校 | 2021-08-13 | — | — | CN | claimed |
| CN-112279842-A | Andrographolide derivative with platelet aggregation resisting activity and preparation method thereof | 谢天龙 | 2021-01-29 | — | — | CN | claimed |
| CN-112151853-A | Battery pole piece with melting recombination characteristic and lithium ion battery comprising same | 浙江锋锂新能源科技有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-111217747-A | Preparation method of pamaquine | 济南韶远医药技术有限公司 | 2020-06-02 | — | — | CN | claimed |
| CN-110105337-A | A kind of quinolines triarylamine and preparation method thereof | 湖南大学 | 2019-08-09 | — | — | CN | claimed |
| EP-2182914-B1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'ORÉAL (FR) | 2017-11-08 | — | — | EP | claimed |
| EP-3096735-A1 | GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME | Combe International Ltd. (US) | 2016-11-30 | — | — | EP | claimed |
| EP-0728466-B1 | Keratinous fibers oxidation dyeing composition comprising an oxidation base, an indolic coupler and an additional heterocyclic coupler and dyeing process | OREAL (FR) | 2000-06-14 | — | — | EP | claimed |
| US-6074438-A | AN OXIDATIVE HAIR DYE MIXTURE COMPRISING PRIMARY INTERMEDIATE AND A COUPLER FORMING AN OXIDATIVE HAIR DYE IN THE PRESENCE OF AN OXIDIZING AGENT | BRISTOL-MYERS SQUIBB CO. (US) | 2000-06-13 | — | — | US | claimed |
| WO-1999051228-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 1999-10-14 | — | — | WO | claimed |
| WO-1999032068-A2 | NEW DEVELOPER COMBINATIONS FOR OXIDATION COLOURING AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-07-01 | — | — | WO | claimed |
| US-5785717-A | Composition for the oxidation dyeing of keratin fibers, comprising a diaminopyrazole derivative and a heterocyclic coupler, and dyeing process | L'OREAL (FR) | 1998-07-28 | — | — | US | claimed |
| US-5769903-A | Composition for the oxidation dyeing of keratin fibers, comprising an oxidation base, an indole coupler and an additional heterocyclic coupler, and dyeing process | L'OREAL (FR) | 1998-06-23 | — | — | US | claimed |
| EP-0728464-B1 | Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process | OREAL (FR) | 1997-07-30 | — | — | EP | claimed |
| CN-1137374-A | Composition for oxidation dyeing of keratin fibers, comprising oxidation base, indole coupler and additional heterocyclic coupler, and dyeing process | OREAL (FR) | 1996-12-11 | — | — | CN | claimed |
| EP-0728464-A1 | Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| EP-0728466-A1 | Keratinous fibers oxidation dyeing composition comprising an oxidation base, an indolic coupler and an additional heterocyclic coupler and dyeing process | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |