SCHEMBL4549432

SCHEMBL4549432

CC1(C)c2ccccc2-c2ccc(-c3ccc4cc(-c5ccc(-c6cccc7c6oc6ccccc67)cc5)c5ccccc5c4c3)cc21

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.44
PRKDC P78527 5/20 0.37
GGPS1 O95749 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.33
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
AVPR1A P37288 1/20 0.31
ALK Q9UM73 2/20 0.31
ATM Q13315 1/20 0.31
PDK2 Q15119 1/20 0.31
PGR P06401 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17069905 0.89 ALOX5 (0.43) ALOX5PRKDCGGPS1PTGES2MEN1
SCHEMBL4549437 0.89 ALOX5 (0.46) ALOX5PRKDCGGPS1PTGES2PIK3CD
SCHEMBL4549397 0.89 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2MEN1
SCHEMBL16017825 0.89 ALOX5 (0.56) ALOX5PRKDCGGPS1PTGES2MEN1
SCHEMBL17069898 0.88 ALOX5 (0.46) ALOX5PRKDCGGPS1PTGES2MEN1
SCHEMBL17069904 0.88 ALOX5 (0.46) ALOX5PRKDCGGPS1PTGES2MEN1
SCHEMBL12324541 0.87 ALOX5 (0.57) ALOX5PRKDCGGPS1PTGES2MEN1
SCHEMBL17069911 0.87 ALOX5 (0.46) ALOX5PRKDCGGPS1PTGES2MEN1
SCHEMBL18826110 0.87 ALOX5 (0.49) ALOX5PRKDCGGPS1PTGES2MEN1
SCHEMBL18086150 0.86 ALOX5 (0.53) ALOX5PRKDCGGPS1PTGES2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885PRKDC 4132/4885GGPS1 1183/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885PRKDC 4132/4885GGPS1 1183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.