SCHEMBL4549438

SCHEMBL4549438

Cc1ccc(-c2ccc3cc(-c4ccc(-c5cccc6c5oc5ccccc56)cc4)c4ccccc4c3c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.50
MAOB P27338 4/20 0.40
TNKS O95271 1/20 0.40
PARP1 P09874 1/20 0.40
TNKS2 Q9H2K2 1/20 0.40
PARP2 Q9UGN5 1/20 0.40
ADORA3 P0DMS8 2/20 0.39
GGPS1 O95749 1/20 0.38
GPR84 Q9NQS5 1/20 0.38
PRKDC P78527 3/20 0.38
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
PTPRF P10586 1/20 0.37
PTPN2 P17706 1/20 0.37
PTPN1 P18031 1/20 0.37
MAOA P21397 1/20 0.36
PTGES2 Q9H7Z7 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
RET P07949 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549414 0.92 ALOX5 (0.52) ALOX5MAOBTNKSPARP1TNKS2
SCHEMBL4549423 0.91 ALOX5 (0.53) ALOX5MAOBGGPS1GPR84PRKDC
SCHEMBL4549428 0.91 ALOX5 (0.53) ALOX5MAOBGGPS1GPR84PRKDC
SCHEMBL4549429 0.90 ALOX5 (0.52) ALOX5MAOBGGPS1GPR84PRKDC
SCHEMBL26564260 0.90 ALOX5 (0.55) ALOX5MAOBTNKSPARP1TNKS2
SCHEMBL4549433 0.89 ALOX5 (0.51) ALOX5GGPS1GPR84PRKDCPTGES2
SCHEMBL4549431 0.89 ALOX5 (0.51) ALOX5MAOBGGPS1PRKDCMAPT
SCHEMBL4549427 0.87 ALOX5 (0.52) ALOX5GGPS1GPR84PRKDCPTGES2
SCHEMBL4549435 0.87 ALOX5 (0.47) ALOX5GGPS1GPR84PRKDCMAPT
SCHEMBL4549436 0.87 ALOX5 (0.47) ALOX5MAOBTNKSPARP1TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-9406889-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-02 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-18 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-8968888-B2 Phenanthrene compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120104369-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885MAOB 966/4885TNKS 2929/4885
US-20150171333-A1 Phenanthrene Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device MC1R, NR2E3, RPS19 ALOX5 3393/4885MAOB 966/4885TNKS 2929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.