Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.47 |
| ▸ | MEN1 | O00255 | 12/20 | 0.47 |
| ▸ | HTT | P42858 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | GAA | P10253 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16039766 | 1.00 | MAPT (0.47) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL28732433 | 0.83 | KMT2A (0.48) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL16039451 | 0.82 | EPHX2 (0.58) | MAPTKMT2AMEN1NPSR1TP53 | |
| SCHEMBL16039450 | 0.82 | EPHX2 (0.58) | MAPTKMT2AMEN1NPSR1TP53 | |
| SCHEMBL16039616 | 0.81 | MAPT (0.50) | MAPTKMT2AMEN1NPSR1TP53 | |
| SCHEMBL16084137 | 0.81 | MAPT (0.50) | MAPTKMT2AMEN1NPSR1TP53 | |
| SCHEMBL16039617 | 0.81 | MAPT (0.50) | MAPTKMT2AMEN1NPSR1TP53 | |
| SCHEMBL19244894 | 0.80 | MAPT (0.70) | MAPTKMT2AMEN1HTTNPSR1 | |
| SCHEMBL4549465 | 0.80 | MAPT (0.49) | MAPTKMT2AMEN1NPSR1TP53 | |
| SCHEMBL31483978 | 0.79 | MAPT (0.60) | MAPTKMT2AMEN1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212150-B2 | Process for the preparation of certain triaryl pesticide intermediates | DOW AGROSCIENCES LLC (US) | 2015-12-15 | — | — | US | disclosed |
| WO-2014163933-A1 | PROCESS FOR PREPARATION OF TRIARYL PESTICIDE INTERMEDIATE | DOW AGROSCIENCES LLC (US) | 2014-10-09 | — | — | WO | disclosed |
| US-20140275557-A1 | PROCESS FOR THE PREPARATION OF CERTAIN TRIARYL PESTICIDE INTERMEDIATES | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DDT, ACHE, NANP | MAPT 2297/4885KMT2A 2528/4885MEN1 4826/4885 |
| US-20140275557-A1 | PROCESS FOR THE PREPARATION OF CERTAIN TRIARYL PESTICIDE INTERMEDIATES | DDT, POR, CYP4F3 | MAPT 4059/4885KMT2A 1642/4885MEN1 3040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.