Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15250869 | 0.74 | CSNK1A1 (0.43) | CSNK1A1CLK4DHFR | |
| SCHEMBL21593668 | 0.74 | CSNK1A1 (0.43) | CSNK1A1CLK4DHFRLMNA | |
| SCHEMBL4549885 | 0.73 | NPC1 (0.35) | — | |
| SCHEMBL30042167 | 0.70 | TLR8 (0.46) | CSNK1A1CLK4 | |
| SCHEMBL15046129 | 0.67 | KIT (0.32) | — | |
| SCHEMBL18476604 | 0.67 | STK17B (0.31) | — | |
| SCHEMBL2596810 | 0.67 | CSNK1A1 (0.46) | CSNK1A1CLK4LMNA | |
| SCHEMBL1774133 | 0.66 | NUDT1 (0.57) | DHFR | |
| SCHEMBL10221991 | 0.66 | MEN1 (0.32) | — | |
| SCHEMBL22612180 | 0.66 | CYP4F2 (0.44) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012061156-A1 | CDK INHIBITORS | TAVARES FRANCIS X (US) | 2012-05-10 | — | — | WO | disclosed |