Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13739574 | 1.00 | PTGS2 (0.56) | PTGS2F10 | |
| SCHEMBL117112 | 1.00 | PTGS2 (0.56) | PTGS2F10 | |
| SCHEMBL19647436 | 0.90 | PTGS2 (0.49) | PTGS2F10 | |
| SCHEMBL15110646 | 0.90 | PTGS2 (0.49) | PTGS2F10 | |
| SCHEMBL19647424 | 0.89 | PTGS2 (0.48) | PTGS2F10 | |
| SCHEMBL15067486 | 0.89 | F10 (0.52) | PTGS2F10 | |
| SCHEMBL15067488 | 0.89 | F10 (0.52) | PTGS2F10 | |
| SCHEMBL21278616 | 0.89 | PTGS2 (0.48) | PTGS2F10 | |
| SCHEMBL13737045 | 0.89 | PTGS2 (0.48) | PTGS2F10 | |
| SCHEMBL13737317 | 0.89 | PTGS2 (0.48) | PTGS2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598403-B2 | Process for the preparation of rivaroxaban | AMNEAL PHARMACEUTICALS LLC (US) | 2017-03-21 | — | — | US | claimed |
| US-20160194309-A1 | A Process For The Preparation Of Rivaroxaban | AMNEAL PHARMACEUTICALS LLC | 2016-07-07 | — | — | US | claimed |
| WO-2015026761-A1 | A PROCESS FOR THE PREPARATION OF RIVAROXABAN | AMNEAL PHARMACEUTICALS LLC (US) | 2015-02-26 | — | — | WO | claimed |
| EP-2613787-A2 | PROCESSES FOR THE PREPARATION OF 4-{4-[5(S)-(AMINOMETHYL)-2-OXO-1,3-OXAZOLIDIN-3-YL]PHENYL} MORPHOLIN-3-ONE | Symed Labs Limited (IN) | 2013-07-17 | — | — | EP | claimed |
| US-20130172554-A1 | PROCESSES FOR THE PREPARATION OF 4-MORPHOLIN-3-ONE | SYMED LABS LIMITED (IN) | 2013-07-04 | — | — | US | claimed |
| WO-2012032533-A2 | PROCESSES FOR THE PREPARATION OF 4-{4-[5(S)-(AMINOMETHYL)-2-OXO-1,3-OXAZOLIDIN-3-YL]PHENYL} MORPHOLIN-3-ONE | SYMED LABS LIMITED (IN) | 2012-03-15 | — | — | WO | claimed |
| CN-112409286-B | Synthesis method of N-substituted phenyl-5-hydroxymethyl-2-oxazolidinone | 杭州迪克科技有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-112409286-A | Synthesis method of N-substituted phenyl-5-hydroxymethyl-2-oxazolidinone | 杭州迪克科技有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112114057-A | Method for separating and measuring rivaroxaban and related substances thereof by using liquid chromatography | 北京万全德众医药生物技术有限公司 | 2020-12-22 | — | — | CN | disclosed |
| EP-2705028-B1 | PROCESS FOR THE PREPARATION OF A RIVAROXABAN AND INTERMEDIATES FORMED IN SAID PROCESS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2019-08-21 | — | — | EP | disclosed |
| EP-2705028-B1 | PROCESS FOR THE PREPARATION OF A RIVAROXABAN AND INTERMEDIATES FORMED IN SAID PROCESS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2019-08-21 | — | — | EP | disclosed |
| US-9598403-B2 | Process for the preparation of rivaroxaban | AMNEAL PHARMACEUTICALS LLC (US) | 2017-03-21 | — | — | US | disclosed |
| US-9556163-B2 | Process for the preparation of a rivaroxaban and intermediates formed in said process | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2017-01-31 | — | — | US | disclosed |
| EP-2705028-A1 | PROCESS FOR THE PREPARATION OF A RIVAROXABAN AND INTERMEDIATES FORMED IN SAID PROCESS | Egis Gyógyszergyár Nyilvánosan Müködö Részvény-Társaság (HU) | 2014-03-12 | — | — | EP | disclosed |
| EP-2697209-A1 | METHOD FOR THE PREPARATION OF SUBSTITUTED OXAZOLIDINONES | Sandoz AG (CH) | 2014-02-19 | — | — | EP | disclosed |
| EP-2613787-A2 | PROCESSES FOR THE PREPARATION OF 4-{4-[5(S)-(AMINOMETHYL)-2-OXO-1,3-OXAZOLIDIN-3-YL]PHENYL} MORPHOLIN-3-ONE | Symed Labs Limited (IN) | 2013-07-17 | — | — | EP | disclosed |
| US-20130172554-A1 | PROCESSES FOR THE PREPARATION OF 4-MORPHOLIN-3-ONE | SYMED LABS LIMITED (IN) | 2013-07-04 | — | — | US | disclosed |
| WO-2012153155-A1 | PROCESS FOR THE PREPARATION OF A RIVAROXABAN AND INTERMEDIATES FORMED IN SAID PROCESS | EGIS GYÓGYSZERGYÁR NYILVÃNOSAN MÜKÖDÖ RÉSZVÉNY-TÁRSASÁG (HU) | 2012-11-15 | — | — | WO | disclosed |
| WO-2012140061-A1 | METHOD FOR THE PREPARATION OF SUBSTITUTED OXAZOLIDINONES | SANDOZ AG (CH) | 2012-10-18 | — | — | WO | disclosed |
| WO-2012032533-A2 | PROCESSES FOR THE PREPARATION OF 4-{4-[5(S)-(AMINOMETHYL)-2-OXO-1,3-OXAZOLIDIN-3-YL]PHENYL} MORPHOLIN-3-ONE | SYMED LABS LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172554-A1 | PROCESSES FOR THE PREPARATION OF 4-MORPHOLIN-3-ONE | TYR, CYP1B1, AAAS | PTGS2 1680/4885F10 4199/4885 |
| US-20160194309-A1 | A Process For The Preparation Of Rivaroxaban | TFPI, VKORC1, VKORC1L1 | PTGS2 1693/4885F10 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.