Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550036 | 0.98 | HDAC6 (0.41) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2619282 | 0.88 | HDAC6 (0.50) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2611306 | 0.86 | HDAC6 (0.52) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL10284845 | 0.84 | TNF (0.43) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2116350 | 0.83 | HDAC6 (0.55) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2117312 | 0.83 | HDAC6 (0.45) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4550099 | 0.79 | MCL1 (0.54) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2611295 | 0.79 | HDAC3 (0.44) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2611340 | 0.78 | RAB9A (0.43) | HDAC6HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2117041 | 0.78 | HDAC6 (0.44) | HDAC6HDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054332-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |