Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118644 | 0.85 | HDAC6 (0.46) | SMPD1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL2619360 | 0.84 | SMPD1 (0.43) | SMPD1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL4550059 | 0.82 | MAPT (0.45) | SMPD1HDAC6HDAC1HDAC8 | |
| SCHEMBL4550180 | 0.82 | SMPD1 (0.56) | SMPD1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL10268001 | 0.81 | HDAC6 (0.51) | PLAUHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL2619364 | 0.81 | HDAC6 (0.46) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2116432 | 0.81 | HDAC6 (0.56) | SMPD1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL2619419 | 0.80 | ALDH1A1 (0.43) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4550103 | 0.80 | HDAC8 (0.46) | SMPD1HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL2117586 | 0.79 | HDAC8 (0.46) | HDAC6HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054332-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |