Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ACACB | O00763 | 4/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550821 | 0.93 | GSK3B (0.59) | GSK3BMAPTACACBSCN9AGSK3A | |
| SCHEMBL4550508 | 0.91 | GSK3B (0.49) | GSK3BMAPTACACBSCN9AGSK3A | |
| SCHEMBL2713653 | 0.88 | GSK3B (0.50) | GSK3BMAPTACACBSCN9AGSK3A | |
| SCHEMBL2716385 | 0.88 | GSK3B (0.50) | GSK3BMAPTACACBSCN9AGSK3A | |
| SCHEMBL2716135 | 0.88 | SCN9A (0.52) | GSK3BMAPTACACBSCN9AGSK3A | |
| SCHEMBL2715577 | 0.87 | GSK3B (0.51) | GSK3BMAPTACACBSCN9AGSK3A | |
| SCHEMBL2718053 | 0.85 | GSK3B (0.60) | GSK3BMAPTACACBSCN9AGSK3A | |
| SCHEMBL2713575 | 0.83 | ACACB (0.50) | GSK3BMAPTACACBSCN9AGSK3A | |
| SCHEMBL18266121 | 0.82 | GSK3B (0.45) | GSK3BMAPTACACBSCN9AGSK3A | |
| SCHEMBL2713908 | 0.82 | GSK3B (0.61) | GSK3BMAPTACACBSCN9AGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053186-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-04-26 | — | — | WO | disclosed |