Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GSK3A | P49840 | 5/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550316 | 0.91 | GSK3B (0.50) | GSK3BMAPTGSK3ASCN9AACACB | |
| SCHEMBL4550821 | 0.91 | GSK3B (0.59) | GSK3BMAPTGSK3ASCN9AACACB | |
| SCHEMBL2717461 | 0.89 | GSK3B (0.49) | GSK3BMAPTGSK3ASCN9AACACB | |
| SCHEMBL2715934 | 0.89 | GSK3B (0.49) | GSK3BMAPTGSK3ASCN9AACACB | |
| SCHEMBL2715674 | 0.88 | SCN9A (0.51) | GSK3BMAPTGSK3ASCN9AACACB | |
| SCHEMBL2716909 | 0.87 | GSK3B (0.49) | GSK3BMAPTGSK3ASCN9AACACB | |
| SCHEMBL2714056 | 0.87 | GSK3B (0.49) | GSK3BMAPTGSK3ASCN9AACACB | |
| SCHEMBL2718053 | 0.83 | GSK3B (0.60) | GSK3BMAPTGSK3ASCN9AACACB | |
| SCHEMBL2715502 | 0.83 | GSK3B (0.48) | GSK3BMAPTGSK3ASCN9AACACB | |
| SCHEMBL4550807 | 0.83 | GSK3B (0.46) | GSK3BMAPTGSK3ASCN9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053186-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-04-26 | — | — | WO | disclosed |