SCHEMBL4550370

SCHEMBL4550370

CCN1CC(C)OC(C)C1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.56
EBP Q15125 2/20 0.56
PDK1 Q15118 1/20 0.43
KDM4E B2RXH2 3/20 0.41
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
CYP2A13 Q16696 1/20 0.39
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36
DRD3 P35462 1/20 0.36
KCNH2 Q12809 1/20 0.36
ATM Q13315 1/20 0.36
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11962148 1.00 SIGMAR1 (0.56) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL12125120 1.00 SIGMAR1 (0.56) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL12125047 1.00 SIGMAR1 (0.56) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL12617065 0.85 EBP (0.44) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL9922437 0.79 SIGMAR1 (0.69) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL22858956 0.79 SIGMAR1 (0.69) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL10129761 0.79 SIGMAR1 (0.69) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL10129057 0.79 SIGMAR1 (0.69) SIGMAR1EBPPDK1KDM4EHTT
SCHEMBL31495434 0.77 EBP (0.36) SIGMAR1EBPATM
SCHEMBL17012154 0.76 SIGMAR1 (0.48) SIGMAR1EBPPDK1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3227234-B1 SILICOALUMINOPHOSPHATE MOLECULAR SIEVES USING AN ORGANO-1-OXA-4-AZONIUMCYCLOHEXANE COMPOUND UOP LLC (US) 2021-05-26 EP claimed
CN-112794851-A 3- (pyridine-3-yl) -7-azaindole derivative PI3K delta inhibitor and preparation method and application thereof 复旦大学 2021-05-14 CN claimed
US-20180258058-A1 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS UOP LLC (US) 2018-09-13 US claimed
US-9815706-B2 Zeolites using an organo-1-oxa-4-azoniumcyclohexane compound UOP LLC (US) 2017-11-14 US claimed
EP-3227266-A2 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS UOP LLC (US) 2017-10-11 EP claimed
US-9751772-B2 Aluminophosphate molecular sieves using an organo-1-oxa-4-azoniumcyclohexane compound UOP LLC (US) 2017-09-05 US claimed
US-20170044120-A1 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS UOP LLC (US) 2017-02-16 US claimed
US-9522896-B2 Organo-1-oxa-4-azonium cyclohexane compounds UOP LLC (US) 2016-12-20 US claimed
US-20160159656-A1 ALUMINOPHOSPHATE MOLECULAR SIEVES USING AN ORGANO-1-OXA-4-AZONIUMCYCLOHEXANE COMPOUND UOP LLC 2016-06-09 US claimed
US-20160159760-A1 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS UOP LLC 2016-06-09 US claimed
US-20160159655-A1 ZEOLITES USING AN ORGANO-1-OXA-4-AZONIUMCYCLOHEXANE COMPOUND UOP LLC 2016-06-09 US claimed
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 WO disclosed
WO-2023183520-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER A2A PHARMACEUTICALS, INC. (US) 2023-09-28 WO disclosed
WO-2023072273-A1 POLYCYCLIC COMPOUND AS CBL-B INHIBITOR 先声再明医药有限公司 2023-05-04 WO disclosed
US-20230097358-A1 INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS, INC. 2023-03-30 US disclosed
EP-0103277-A1 Quaternary ammonium salts of benzofuran derivatives and fungicides containing them BASF Aktiengesellschaft (DE) 1984-03-21 EP disclosed
US-4421914-A IMMUNE FUNCTION REGULATORS TEIJIN LIMITED (JP) 1983-12-20 US disclosed
US-4376776-A Dibenzofuran derivatives and their use for controlling fungi BASF AKTIENGESELLSCHAFT (DE) 1983-03-15 US disclosed
EP-0057362-A1 Dibenzofurane derivatives, process for their preparation and their use as fungicides BASF Aktiengesellschaft (DE) 1982-08-11 EP disclosed
EP-0049902-A2 Novel thiazolo(3,2-a)pyrimidines, derivatives thereof, processes for production thereof, and pharmaceutical use thereof TEIJIN LIMITED (JP) 1982-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160159760-A1 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS OXSR1, OXER1, OCIAD1 SIGMAR1 238/4885EBP 1172/4885PDK1 1344/4885
US-20230097358-A1 INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE LRRK2, CRBN, MDM2 SIGMAR1 3941/4885EBP 4209/4885PDK1 1366/4885
US-20180258058-A1 ORGANO-1-OXA-4-AZONIUM CYCLOHEXANE COMPOUNDS OXSR1, OXER1, OCIAD1 SIGMAR1 238/4885EBP 1172/4885PDK1 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.