Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18266733 | 0.87 | ACACB (0.50) | ACACBKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL2715049 | 0.86 | ACACB (0.54) | ACACBKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL2715048 | 0.86 | ACACB (0.54) | ACACBKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL2719067 | 0.83 | ACACB (0.58) | ACACBKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL19736119 | 0.83 | FDPS (0.64) | ACACBFDPSMAPKAPK2JAK2JAK1 | |
| SCHEMBL2716398 | 0.82 | ACACB (0.52) | ACACBKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL2717673 | 0.81 | ACACB (0.61) | ACACBKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL2717426 | 0.81 | ACACB (0.56) | ACACBKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL2717269 | 0.81 | ACACB (0.56) | ACACBKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL18266725 | 0.81 | ACACB (0.56) | ACACBKMT2AMEN1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012053186-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-04-26 | — | — | WO | disclosed |