SCHEMBL4550625

SCHEMBL4550625

O=C(O)C(Cl)=C(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11514988 1.00 ALDH1A1 (0.44) ALDH1A1TP53TSHR
Butane SCHEMBL10439100 0.87 TSHR (0.35) ALDH1A1TP53TSHR
SCHEMBL11611689 0.73 ALDH1A1 (0.42) ALDH1A1TP53TSHR
SCHEMBL133084 0.73 ALDH1A1 (0.42) ALDH1A1TP53TSHR
Hydrogen Peroxide SCHEMBL2045199 0.71 CA1 (0.36) ALDH1A1TP53TSHR
SCHEMBL1250948 0.71 CA1 (0.36) ALDH1A1TP53TSHR
SCHEMBL1250950 0.71 CA1 (0.36) ALDH1A1TP53TSHR
Hydrogen Peroxide SCHEMBL2045201 0.71 CA1 (0.36) ALDH1A1TP53TSHR
Hydrogen Peroxide SCHEMBL2045196 0.71 CA1 (0.36) ALDH1A1TP53TSHR
SCHEMBL11317589 0.71 CA1 (0.36) ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
US-7514386-B2 Chlorinated promoters for vanadium-based polymerization catalysts POLIMERI EUROPA S.P.A. (IT) 2009-04-07 US disclosed
US-20050274928-A1 Chlorinated promoters for vanadium-based polymerization catalysts POLIMERI EUROPA S.P.A. (IT) 2005-12-15 US disclosed
EP-1600462-A2 Chlorinated promoters for vanadium-based polymerization catalysts Polimeri Europa S.p.A. (IT) 2005-11-30 EP disclosed
US-4361686-A Preparation of copolymers of ethylene with at least one other 1-monoolefin and an optional unconjugated diene CHEMISCHE WERKE HUELS, AKTIENGESELLSCHAFT (DE) 1982-11-30 US disclosed
US-4181790-A A 2,3,4,4-TETRACHLORO-3-BUTENOATE Chemische Werke Huels, Aktiengellschaft (DE) 1980-01-01 US disclosed
US-4175095-A Process for the manufacture of pentachlorovinylacetyl chloride CHEMISCHE WERKE HULS, A.G. (DE) 1979-11-20 US disclosed