Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | HPD | P32754 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551151 | 0.87 | CYP1A2 (0.51) | CYP1A2FFAR1TSHRSMN1; SMN2GSTP1 | |
| SCHEMBL4393122 | 0.82 | CYP1A2 (0.61) | CYP1A2FFAR1TSHRSMN1; SMN2PTGER4 | |
| SCHEMBL4398280 | 0.79 | GYS1 (0.49) | CYP1A2FFAR1TSHRSMN1; SMN2PTGER4 | |
| SCHEMBL4391236 | 0.78 | CYP1A2 (0.56) | CYP1A2FFAR1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL14514269 | 0.78 | CYP1A2 (0.65) | CYP1A2FFAR1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL4391311 | 0.78 | CYP1A2 (0.58) | CYP1A2FFAR1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL4392867 | 0.76 | FFAR1 (0.53) | CYP1A2FFAR1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL4392754 | 0.76 | MAOB (0.52) | CYP1A2TSHRPTGER4MEN1POLB | |
| SCHEMBL4392762 | 0.75 | SMPD1 (0.60) | CYP1A2FFAR1TSHRSMN1; SMN2SMPD1 | |
| SCHEMBL4396609 | 0.73 | SMPD1 (0.55) | CYP1A2FFAR1TSHRSMN1; SMN2CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067109-B1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2009-12-09 | — | — | EP | claimed |