Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | FAP | Q12884 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550697 | 1.00 | DPP4 (0.61) | DPP4DPP8DPP7DPP9ACE | |
| Hydrochloric Acid SCHEMBL4399414 | 0.99 | DPP4 (0.61) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL8345171 | 0.90 | DPP4 (0.66) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4387254 | 0.86 | DPP4 (0.56) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL4392074 | 0.82 | DPP4 (0.44) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL4400632 | 0.77 | DPP4 (0.60) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL5228197 | 0.76 | DPP4 (1.00) | DPP4DPP8DPP7DPP9ACE | |
| Hydrochloric Acid SCHEMBL4399397 | 0.76 | DPP4 (0.59) | DPP4DPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL1842316 | 0.76 | DPP4 (0.98) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL16161427 | 0.75 | DPP4 (0.72) | DPP4DPP8DPP7DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554256-B1 | PIPERIDINO PYRIMIDINE DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK & CO INC (US) | 2009-12-09 | — | — | EP | disclosed |