Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2713170 | 0.98 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EMEN1USP2 | |
| Hydrochloric Acid SCHEMBL15669771 | 0.88 | AAK1 (0.38) | ALDH1A1MAPTKDM4EMEN1USP2 | |
| SCHEMBL15351086 | 0.84 | HTR2A (0.43) | MAPTKDM4EHSP90AA1HSP90AB1AAK1 | |
| SCHEMBL15350441 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EMEN1USP2 | |
| Hydrochloric Acid SCHEMBL15669839 | 0.84 | MAPK1 (0.36) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15351130 | 0.83 | HTR2A (0.44) | MAPTKDM4EHSP90AA1HSP90AB1AAK1 | |
| SCHEMBL15670650 | 0.77 | CYP17A1 (0.35) | MAPTAAK1CYP17A1CNR2 | |
| Hydrochloric Acid SCHEMBL15351106 | 0.77 | AAK1 (0.42) | ALDH1A1MAPTKDM4EMEN1USP2 | |
| SCHEMBL15350197 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EMEN1USP2 | |
| Hydrochloric Acid SCHEMBL15351004 | 0.76 | CYP17A1 (0.34) | ALOX15AAK1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140336377-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2014-11-13 | — | — | US | disclosed |
| US-20140336377-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2014-11-13 | — | — | US | disclosed |
| WO-2012053186-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | RAQUALIA PHARMA INC. (JP) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336377-A1 | ARYLAMIDE DERIVATIVES AS TTX-S BLOCKERS | SCN2B, SCN1B, SCN2A | ALDH1A1 1358/4885MAPT 3185/4885KDM4E 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.