Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL821874 | 0.71 | CA12 (0.32) | CYP1A2MAPK1CA12CA1CA2 | |
| SCHEMBL14804679 | 0.65 | — | — | |
| SCHEMBL1005731 | 0.65 | PIK3CD (0.52) | PIK3CDCYP1A2MAPK1CA12CA1 | |
| SCHEMBL91203 | 0.65 | — | — | |
| SCHEMBL11832323 | 0.65 | — | — | |
| Fluoride Ion SCHEMBL821757 | 0.65 | CA12 (0.32) | CYP1A2MAPK1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL822288 | 0.65 | CA12 (0.32) | CYP1A2MAPK1CA12CA1CA2 | |
| Bromide SCHEMBL821919 | 0.65 | CA12 (0.32) | CYP1A2MAPK1CA12CA1CA2 | |
| SCHEMBL25813705 | 0.62 | — | — | |
| SCHEMBL30665948 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612009-B2 | Process for homo-or copolymerization of conjugated olefines | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20060142145-A1 | Process for homo-or copolymerization of conjugated olefines | TRINSEO EUROPE GMBH (CH) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142145-A1 | Process for homo-or copolymerization of conjugated olefines | ETFB, F12, F2 | PIK3CD 384/4885CYP1A2 2762/4885MAPK1 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.