Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.60 |
| ▸ | IDO1 | P14902 | 2/20 | 0.60 |
| ▸ | AGXT | P21549 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.56 |
| ▸ | CMA1 | P23946 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | LPO | P22079 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2099512 | 0.82 | CHRM2 (0.66) | TAAR1IDO1AGXTCHRM2CHRM1 | |
| SCHEMBL723511 | 0.82 | TAAR1 (0.77) | TAAR1IDO1AGXTCHRM2CHRM1 | |
| SCHEMBL30080050 | 0.82 | TAAR1 (0.77) | TAAR1IDO1AGXTCHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL1792278 | 0.81 | TAAR1 (0.58) | TAAR1IDO1AGXTCHRM2CHRM1 | |
| Bromide SCHEMBL3939438 | 0.81 | TAAR1 (0.58) | TAAR1IDO1AGXTCHRM2CHRM1 | |
| SCHEMBL12497 | 0.80 | TAAR1 (0.62) | TAAR1IDO1AGXTCHRM2CHRM1 | |
| SCHEMBL27583382 | 0.80 | TAAR1 (0.62) | TAAR1IDO1AGXTCHRM2CHRM1 | |
| SCHEMBL29908907 | 0.80 | TAAR1 (0.62) | TAAR1IDO1AGXTCHRM2CHRM1 | |
| SCHEMBL9170387 | 0.79 | TAAR1 (0.67) | TAAR1IDO1AGXTCHRM2CHRM1 | |
| SCHEMBL1145614 | 0.78 | TAAR1 (0.60) | TAAR1IDO1AGXTCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2130820-A1 | Antipruritics | SHIONOGI & CO., LTD. (JP) | 2009-12-09 | — | — | EP | disclosed |