Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | BRD2 | P25440 | 2/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415422 | 0.86 | MCL1 (0.44) | BRD4BRD2BRD3PI4KAMCL1 | |
| SCHEMBL26663815 | 0.73 | MCL1 (0.54) | MCL1MAPK1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15881071 | 0.72 | MCL1 (0.53) | MCL1MAPK1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4607774 | 0.72 | MCL1 (0.46) | MCL1ALDH1A1TP53 | |
| SCHEMBL4166429 | 0.71 | BRD4 (0.51) | BRD4BRD2BRD3PI4KBPI4KA | |
| SCHEMBL27422587 | 0.69 | BRD4 (0.58) | BRD4BRD2BRD3PI4KAHTT | |
| SCHEMBL27422584 | 0.69 | BRD4 (0.58) | BRD4BRD2BRD3PI4KAHTT | |
| SCHEMBL2304762 | 0.69 | MCL1 (0.49) | MCL1MAPK1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2305822 | 0.68 | MCL1 (0.51) | MCL1MAPK1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4607766 | 0.68 | MCL1 (0.44) | MCL1MAPK1HTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156465-A1 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156465-A1 | DERIVATIVES OF BETA-AMINO ACID AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | DPP4, DPP3, DPP7 | BRD4 2356/4885BRD2 3713/4885BRD3 3996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.