Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.51 |
| ▸ | BRD2 | P25440 | 2/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593184 | 0.82 | BRD4 (0.53) | BRD4BRD2BRD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8490919 | 0.82 | ALDH1A1 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL995294 | 0.78 | ALDH1A1 (0.68) | BRD4BRD2BRD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL17277267 | 0.78 | ALDH1A1 (0.68) | BRD4BRD2BRD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL17277312 | 0.78 | ALDH1A1 (0.68) | BRD4BRD2BRD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL27422587 | 0.76 | BRD4 (0.58) | BRD4BRD2BRD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL27422584 | 0.76 | BRD4 (0.58) | BRD4BRD2BRD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL10797764 | 0.75 | APLNR (0.46) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4668508 | 0.74 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2CYP3A4TSHRKMT2A | |
| SCHEMBL3976452 | 0.74 | EHMT2 (0.45) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170898-A1 | Sulphonamide Derivatives as Modulators of the Glucocorticoid Receptor | BENGTSSON MALENA | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170898-A1 | Sulphonamide Derivatives as Modulators of the Glucocorticoid Receptor | NR3C1, NR3C2, NR5A1 | BRD4 2260/4885BRD2 1912/4885BRD3 1730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.