Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259847 | 1.00 | ADRB2 (0.73) | ADRB2CA1CA2HSD17B2 | |
| SCHEMBL4259839 | 1.00 | ADRB2 (0.73) | ADRB2CA1CA2HSD17B2 | |
| SCHEMBL4260745 | 0.93 | ADRB2 (0.62) | ADRB2 | |
| SCHEMBL4260721 | 0.93 | ADRB2 (0.61) | ADRB2 | |
| SCHEMBL4552324 | 0.93 | ADRB2 (0.61) | ADRB2 | |
| SCHEMBL4260747 | 0.93 | ADRB2 (0.62) | ADRB2 | |
| SCHEMBL4260717 | 0.93 | ADRB2 (0.61) | ADRB2 | |
| SCHEMBL4256306 | 0.91 | ADRB2 (0.60) | ADRB2 | |
| SCHEMBL4256308 | 0.91 | ADRB2 (0.60) | ADRB2 | |
| SCHEMBL4258497 | 0.91 | ADRB2 (0.71) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624868-B9 | \"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL]PHENYL DERIVATIVES AS BETA2 AGONISTS | PFIZER LTD (GB) | 2009-08-12 | — | — | EP | disclosed |
| EP-1624868-B1 | \"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL]PHENYL DERIVATIVES AS BETA2 AGONISTS | PFIZER LTD (GB) | 2008-11-12 | — | — | EP | disclosed |