Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807377 | 0.88 | FFAR1 (0.39) | FFAR1FFAR4KCNH2PDGFRBPDGFRA | |
| SCHEMBL2810796 | 0.82 | KCNH2 (0.47) | FFAR1FFAR4KCNH2PDGFRBPDGFRA | |
| SCHEMBL27941324 | 0.79 | KCNH2 (0.45) | FFAR1FFAR4KCNH2PDGFRBPDGFRA | |
| SCHEMBL31484811 | 0.75 | FFAR1 (0.38) | FFAR1FFAR4KCNH2PDGFRBPDGFRA | |
| SCHEMBL28773586 | 0.72 | FFAR1 (0.51) | FFAR1FFAR4HAO1NPC1MAPT | |
| SCHEMBL8752132 | 0.71 | CYP1A2 (0.55) | FFAR1FFAR4KCNH2PDGFRBPDGFRA | |
| SCHEMBL11225320 | 0.71 | CYP1A2 (0.55) | FFAR1FFAR4KCNH2PDGFRBPDGFRA | |
| SCHEMBL19328864 | 0.71 | FFAR1 (0.47) | FFAR1FFAR4KCNH2PDGFRBPDGFRA | |
| SCHEMBL674063 | 0.69 | BACE1 (0.57) | CYP1A2NPC1MAPTRAB9ABACE1 | |
| SCHEMBL2814718 | 0.69 | TP53 (0.39) | FFAR1FFAR4KCNH2PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126700-A1 | HYDROXYLATED TOLANS AND RELATED COMPOUNDS AS COSMETICS OR THERAPEUTICS FOR SKIN CONDITIONS | KENT STATE UNIVERSITY (US) | 2009-10-15 | — | — | WO | claimed |
| WO-2009126700-A1 | HYDROXYLATED TOLANS AND RELATED COMPOUNDS AS COSMETICS OR THERAPEUTICS FOR SKIN CONDITIONS | KENT STATE UNIVERSITY (US) | 2009-10-15 | — | — | WO | disclosed |