Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628332 | 0.90 | NAAA (0.64) | GAAALDH1A1TDP1NAAADRD2 | |
| SCHEMBL14219224 | 0.84 | NAAA (0.69) | GAASMN1; SMN2NAAADRD2DRD4 | |
| SCHEMBL11854068 | 0.81 | NAAA (0.79) | ALDH1A1SMN1; SMN2NAAAHDAC3HDAC4 | |
| SCHEMBL11852545 | 0.81 | NAAA (0.79) | ALDH1A1SMN1; SMN2NAAAHDAC3HDAC4 | |
| SCHEMBL11850039 | 0.81 | NAAA (0.79) | ALDH1A1SMN1; SMN2NAAAHDAC3HDAC4 | |
| SCHEMBL11841161 | 0.81 | NAAA (0.79) | ALDH1A1SMN1; SMN2NAAAHDAC3HDAC4 | |
| SCHEMBL11854495 | 0.81 | NAAA (0.79) | ALDH1A1SMN1; SMN2NAAAHDAC3HDAC4 | |
| SCHEMBL11853375 | 0.81 | NAAA (0.79) | ALDH1A1SMN1; SMN2NAAAHDAC3HDAC4 | |
| SCHEMBL11854927 | 0.81 | NAAA (0.79) | ALDH1A1SMN1; SMN2NAAAHDAC3HDAC4 | |
| SCHEMBL9545406 | 0.81 | NAAA (0.58) | GAAALDH1A1SMN1; SMN2NAAADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057116-A1 | NEW PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | Richter Gedeon NYRT (HU) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008050167-A1 | NEW PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2008-05-02 | — | — | WO | disclosed |