SCHEMBL4551729

SCHEMBL4551729

CC(Cc1cccc(CC(=O)NCc2ccccc2O)c1)NCC(O[Si](C)(C)C(C)(C)C)c1ccc(O)c(CO)c1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4261128 1.00 ADRB2 (0.64) ADRB2
SCHEMBL4261132 1.00 ADRB2 (0.64) ADRB2
SCHEMBL4258497 0.95 ADRB2 (0.71) ADRB2
SCHEMBL4258495 0.95 ADRB2 (0.71) ADRB2
SCHEMBL4257717 0.94 ADRB2 (0.60) ADRB2
SCHEMBL4257710 0.94 ADRB2 (0.60) ADRB2
SCHEMBL4261131 0.92 ADRB2 (0.59) ADRB2
SCHEMBL4261135 0.92 ADRB2 (0.59) ADRB2
SCHEMBL6000569 0.92 ADRB2 (0.59) ADRB2
SCHEMBL4260747 0.91 ADRB2 (0.62) ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1624868-B9 \"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL]PHENYL DERIVATIVES AS BETA2 AGONISTS PFIZER LTD (GB) 2009-08-12 EP disclosed
EP-1624868-B1 \"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL]PHENYL DERIVATIVES AS BETA2 AGONISTS PFIZER LTD (GB) 2008-11-12 EP disclosed