Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552965 | 0.93 | CCR5 (0.65) | CCR5KCNH2 | |
| SCHEMBL14185375 | 0.92 | CCR5 (0.69) | CCR5KCNH2 | |
| SCHEMBL4552548 | 0.92 | CCR5 (0.60) | CCR5KCNH2 | |
| SCHEMBL4551934 | 0.90 | CCR5 (0.65) | CCR5KCNH2 | |
| SCHEMBL14185505 | 0.87 | CCR5 (0.68) | CCR5KCNH2 | |
| SCHEMBL4429198 | 0.86 | CCR5 (0.63) | CCR5KCNH2 | |
| SCHEMBL13052013 | 0.84 | CCR5 (1.00) | CCR5KCNH2 | |
| SCHEMBL13052041 | 0.80 | CCR5 (0.86) | CCR5KCNH2 | |
| SCHEMBL13051992 | 0.80 | CCR5 (0.89) | CCR5KCNH2 | |
| SCHEMBL13878182 | 0.79 | CCR5 (0.90) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088860-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |