Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.81 |
| ▸ | GSK3A | P49840 | 7/20 | 0.48 |
| ▸ | SRC | P12931 | 4/20 | 0.47 |
| ▸ | SYK | P43405 | 4/20 | 0.47 |
| ▸ | SCARB1 | Q8WTV0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599748 | 0.90 | MAPK14 (0.79) | MAPK14GSK3ASRCSYKSCARB1 | |
| SCHEMBL1600941 | 0.89 | MAPK14 (1.00) | MAPK14GSK3ASRCSYKSCARB1 | |
| SCHEMBL1599651 | 0.85 | MAPK14 (0.73) | MAPK14GSK3ASCARB1 | |
| SCHEMBL1600084 | 0.81 | MAPK14 (0.64) | MAPK14GSK3ASRCSYKSCARB1 | |
| SCHEMBL5314960 | 0.80 | MAPK14 (0.65) | MAPK14GSK3ASRCSYKSCARB1 | |
| SCHEMBL4419926 | 0.80 | MAPK14 (0.83) | MAPK14GSK3ASRCSYKSCARB1 | |
| SCHEMBL1600569 | 0.79 | MAPK14 (0.64) | MAPK14GSK3ASRCSYKSCARB1 | |
| SCHEMBL4949605 | 0.79 | MAPK14 (0.67) | MAPK14GSK3ASRCSYKSCARB1 | |
| SCHEMBL1598842 | 0.79 | MAPK14 (0.81) | MAPK14GSK3ASRCSYKSCARB1 | |
| SCHEMBL5312427 | 0.77 | MAPK14 (1.00) | MAPK14GSK3ASRCSYKSCARB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670787-A4 | CYTOKINE INHIBITORS | KEMIA INC (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-1670787-A2 | CYTOKINE INHIBITORS | Kemia, INC. (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005023761-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2005-03-17 | — | — | WO | disclosed |