Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.65 |
| ▸ | GSK3A | P49840 | 8/20 | 0.46 |
| ▸ | SCARB1 | Q8WTV0 | 3/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599748 | 0.88 | MAPK14 (0.79) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL4418875 | 0.88 | MAPK14 (0.59) | MAPK14GSK3ASCARB1 | |
| SCHEMBL1600084 | 0.85 | MAPK14 (0.64) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL1600569 | 0.84 | MAPK14 (0.64) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL4413523 | 0.82 | MAPK14 (0.58) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL4551970 | 0.80 | MAPK14 (0.81) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL14155409 | 0.79 | MAPK14 (0.59) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL1600941 | 0.79 | MAPK14 (1.00) | MAPK14GSK3ASCARB1SRCSYK | |
| SCHEMBL1600014 | 0.79 | MAPK14 (0.64) | MAPK14GSK3ASCARB1 | |
| SCHEMBL4419926 | 0.79 | MAPK14 (0.83) | MAPK14GSK3ASCARB1SRCSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058990-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-24 | — | — | WO | disclosed |
| WO-2006091862-A2 | CYTOKINE INHIBITORS AND THEIR USE IN THERAPY | KEMIA, INC. (US) | 2006-08-31 | — | — | WO | disclosed |