Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16822326 | 0.75 | KMT2A (0.49) | KMT2AGFERALDH1A1LMNATSHR | |
| SCHEMBL19848406 | 0.74 | KMT2A (0.51) | KMT2AGFERALDH1A1LMNACYP3A4 | |
| SCHEMBL19911432 | 0.72 | KMT2A (0.46) | KMT2AGFERALDH1A1LMNACYP3A4 | |
| SCHEMBL24110391 | 0.70 | GFER (0.45) | KMT2AGFERALDH1A1LMNACYP3A4 | |
| SCHEMBL28794558 | 0.67 | ASAH1 (0.62) | KMT2AGFERLMNAMAPK1 | |
| SCHEMBL29795679 | 0.67 | ASAH1 (0.62) | KMT2AGFERLMNAMAPK1 | |
| SCHEMBL29145084 | 0.66 | ASAH1 (0.47) | KMT2AALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL29795660 | 0.65 | ASAH1 (0.62) | ALDH1A1LMNACYP3A4THRB | |
| SCHEMBL28945618 | 0.65 | ASAH1 (0.62) | ALDH1A1LMNACYP3A4THRB | |
| SCHEMBL2034906 | 0.65 | SIK1 (0.42) | KMT2AALDH1A1LMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040698-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |