Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4552112 | 1.00 | OPRK1 (0.31) | OPRK1 | |
| SCHEMBL16969175 | 0.85 | ESR2 (0.39) | — | |
| SCHEMBL16969177 | 0.85 | ESR2 (0.39) | — | |
| SCHEMBL2353284 | 0.83 | — | — | |
| SCHEMBL2353287 | 0.83 | — | — | |
| SCHEMBL14685956 | 0.81 | TSHR (0.33) | OPRK1 | |
| SCHEMBL2559214 | 0.81 | TSHR (0.33) | OPRK1 | |
| SCHEMBL29878192 | 0.76 | NPC1 (0.32) | — | |
| SCHEMBL7714095 | 0.74 | MAP4K4 (0.35) | — | |
| SCHEMBL2579922 | 0.74 | MAP4K4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2045245-B1 | INREVERSIBLE PROTEIN TYROSINE KINASES INHIBITORS AND THE PREPARATION METHODS AND USES THEREOF | TIAN JIN HEMAY BIO TECH CO LTD (CN) | 2013-10-23 | — | — | EP | disclosed |
| EP-2045245-A1 | INREVERSIBLE PROTEIN TYROSINE KINASES INHIBITORS AND THE PREPARATION METHODS AND USES THEREOF | Tian Jin Hemay Bio-Tech Co., Ltd. (CN) | 2009-04-08 | — | — | EP | disclosed |