SCHEMBL45523

SCHEMBL45523

CC(C)(C)C(Br)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30170231 1.00
SCHEMBL6380221 0.97 ALDH1A1 (0.42)
Iodide SCHEMBL1478059 0.94 ALDH1A1 (0.40)
Iodide SCHEMBL1478057 0.94 ALDH1A1 (0.40)
Acetonitrile SCHEMBL28207157 0.87 ALDH1A1 (0.35)
SCHEMBL11290734 0.81 ALDH1A1 (0.44)
SCHEMBL11335436 0.79
Hydrochloric Acid SCHEMBL11288648 0.79 ALDH1A1 (0.42)
Hydrochloric Acid SCHEMBL11288423 0.79 ALDH1A1 (0.42)
SCHEMBL8872262 0.78 CYP3A4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2596 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073296-A Method and device for rapidly detecting propylene glycol in food 深圳市易瑞生物技术股份有限公司 2022-09-20 CN claimed
EP-3517105-B1 TRANSDERMAL ADHESIVE COMPOSITIONS, DEVICES, AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2021-04-28 EP claimed
CN-107602559-B A method of the asymmetric ciprofloxacin eye drops synthesis of chiral ternary carbocyclic nucleoside caused by Michael's addition 河南师范大学 2019-10-18 CN claimed
EP-2596071-B1 TRANSDERMAL ADHESIVE COMPOSITIONS, DEVICES, AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2019-02-13 EP claimed
EP-2651965-B1 CYCLOSPORINE ANALOGUE MOLECULES MODIFIED AT AMINO ACID 1 AND 3 CONTRAVIR PHARMACEUTICALS INC (US) 2018-12-12 EP claimed
EP-2537834-B1 POLYAZAMACROCYCLIC COMPOUND, AND A PRODUCTION METHOD AND A BIOMEDICAL USE THEREFOR KYUNGPOOK NAT UNIV IND ACADEMIC COOP FOUND (KR) 2018-09-05 EP claimed
CN-107793415-A The synthetic method of Zolpidemtar Trate impurity 湖南省食品药品检验研究院 2018-03-13 CN claimed
CN-107602559-A A kind of method of the asymmetric ciprofloxacin eye drops synthesis of chiral ternary carbocyclic nucleoside triggered by Michael's addition 河南师范大学 2018-01-19 CN claimed
CN-103965047-B The preparation method of 3,3,3-trifluoroacetic acid and ester thereof XI'AN INST. OF MODERN CHEMISTRY (CN) 2015-10-28 CN claimed
US-9079867-B2 Polyazamacrocyclic compound, and a production method and a biomedical use therefor KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-07-14 US claimed
EP-0824126-B1 Preparation of carboxylic acid-containing polyether and biologically active substances derived thereof ENZON INC (US) 2003-06-25 EP claimed
US-20030060657-A1 Process for the preparation of Aceclofenac RUSSINSKY LIMITED 2003-03-27 US claimed
EP-1157004-A1 REGIOSELECTIVE SYNTHESIS OF DTPA DERIVATIVES IDEC PHARMACEUTICALS CORPORATION (US) 2001-11-28 EP claimed
US-6207858-B1 ELIMINATES THE NEED FOR ION EXCHANGE CHROMOTOGRAPHIC SEPARATION OF INTERMEDIATES, USEFUL AS BI-FUNCTIONAL CHELATORS IN RADIOIMMUNOTHERAPY AND IMAGING, DIETHYLENETRIAMINEPENTAACETIC ACID (DTPA), SUITABLE FOR IDEC PHARMACEUTICALS CORPORATION 2001-03-27 US claimed
WO-2000051976-A1 REGIOSELECTIVE SYNTHESIS OF DTPA DERIVATIVES IDEC PHARMACEUTICALS CORPORATION (US) 2000-09-08 WO claimed
EP-0667856-B1 NOVEL VITAMIN D ANALOGUES LEO PHARM PROD LTD (DK) 1998-02-04 EP claimed
EP-0458551-B1 Spiro-isoquinoline-pyrrolidines and analogs thereof useful as aldose reductase inhibitors AMERICAN HOME PROD (US) 1997-12-03 EP claimed
EP-0793643-A1 MATRIX METALLOPROTEASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1997-09-10 EP claimed
WO-1996016027-A1 MATRIX METALLOPROTEASE INHIBITORS SYNTEX (U.S.A.) INC. (US) 1996-05-30 WO claimed
EP-0365324-B1 Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors AMERICAN HOME PROD (US) 1994-05-04 EP claimed