Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20265001 | 0.77 | USP2 (0.46) | USP2SMN1; SMN2ESR2MAPTKDM4E | |
| SCHEMBL31028 | 0.74 | USP2 (0.56) | USP2SMN1; SMN2ESR2MAPTKDM4E | |
| SCHEMBL27669441 | 0.74 | USP2 (0.56) | USP2SMN1; SMN2ESR2MAPTKDM4E | |
| SCHEMBL28688256 | 0.73 | ESR2 (0.41) | USP2SMN1; SMN2ESR2MAPTKDM4E | |
| SCHEMBL795243 | 0.73 | USP2 (0.42) | USP2SMN1; SMN2ESR2NR1H2GPR119 | |
| Ammonia Solution, Strong SCHEMBL27841683 | 0.73 | USP2 (0.55) | USP2SMN1; SMN2ESR2MAPTKDM4E | |
| SCHEMBL2600437 | 0.72 | SMN1; SMN2 (0.56) | USP2SMN1; SMN2ESR2MAPTKDM4E | |
| Ethylene SCHEMBL3832936 | 0.71 | USP2 (0.53) | USP2SMN1; SMN2ESR2MAPTKDM4E | |
| SCHEMBL188772 | 0.71 | HPGD (0.41) | USP2SMN1; SMN2ESR2NR1H2MEN1 | |
| SCHEMBL17481737 | 0.71 | USP2 (0.41) | USP2SMN1; SMN2ESR2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2045245-B1 | INREVERSIBLE PROTEIN TYROSINE KINASES INHIBITORS AND THE PREPARATION METHODS AND USES THEREOF | TIAN JIN HEMAY BIO TECH CO LTD (CN) | 2013-10-23 | — | — | EP | disclosed |
| EP-2045245-A1 | INREVERSIBLE PROTEIN TYROSINE KINASES INHIBITORS AND THE PREPARATION METHODS AND USES THEREOF | Tian Jin Hemay Bio-Tech Co., Ltd. (CN) | 2009-04-08 | — | — | EP | disclosed |