Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL454126 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL450495 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL454469 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL454154 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL453171 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL453407 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL453229 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL454973 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8166522 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL455001 | 0.80 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163946-A1 | New C5a Binding Nucleic Acids | APTARION BIOTECH AG (DE) | 2021-06-03 | — | — | US | disclosed |
| US-10590424-B2 | C5a binding nucleic acids | NOXXON PHARMA AG (DE) | 2020-03-17 | — | — | US | disclosed |
| EP-2802660-B1 | NEW C5A BINDING NUCLEIC ACIDS | APTARION BIOTECH AG (DE) | 2020-02-19 | — | — | EP | disclosed |
| CN-104145018-B | Novel C5 a-binding nucleic acids | 诺松制药股份公司 | 2019-05-10 | — | — | CN | disclosed |
| US-20180223285-A1 | C5a Binding Nucleic Acids | NOXXON PHARMA AG (DE) | 2018-08-09 | — | — | US | disclosed |
| US-9518265-B2 | C5a binding nucleic acids | NOXXON PHARMA AG (DE) | 2016-12-13 | — | — | US | disclosed |
| US-20140364487-A1 | New C5a Binding Nucleic Acids | APTARION BIOTECH AG (DE) | 2014-12-11 | — | — | US | disclosed |
| CN-104145018-A | Novel C5 a-binding nucleic acids | NOXXON PHARMA AG | 2014-11-12 | — | — | CN | disclosed |
| US-8507456-B2 | C5a binding nucleic acids | NOXXON PHARMA AG (DE) | 2013-08-13 | — | — | US | disclosed |
| EP-2562256-A2 | C5a binding nucleic acids | Noxxon Pharma AG (DE) | 2013-02-27 | — | — | EP | disclosed |
| US-20120065254-A1 | C5A binding nucleic acids and the use thereof | NOXXON PHARMA AG (DE) | 2012-03-15 | — | — | US | disclosed |
| US-20110046207-A1 | C5a binding nucleic acids | NOXXON PHARMA AG (DE) | 2011-02-24 | — | — | US | disclosed |
| CN-101809154-A | C5a binding nucleic acids | NOXXON PHARMA AG | 2010-08-18 | — | — | CN | disclosed |