Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19067418 | 0.98 | CETP (0.45) | CETPCSNK1ECNR2CTRC | |
| Ammonia Solution, Strong SCHEMBL28598707 | 0.98 | CETP (0.42) | CETPCSNK1ECNR2CTRCCTSL | |
| SCHEMBL21230427 | 0.95 | CTSK (0.43) | CETPCSNK1ECNR2CTRCCTSL | |
| SCHEMBL31354463 | 0.89 | CETP (0.42) | CETPCSNK1ECTRCSIGMAR1 | |
| SCHEMBL31354493 | 0.89 | CETP (0.42) | CETPCSNK1ECTRCSIGMAR1 | |
| SCHEMBL31354455 | 0.89 | CETP (0.42) | CETPCSNK1ECTRCSIGMAR1 | |
| SCHEMBL31354624 | 0.89 | CETP (0.42) | CETPCSNK1ECTRCSIGMAR1 | |
| SCHEMBL31354576 | 0.89 | CETP (0.42) | CETPCSNK1ECTRCSIGMAR1 | |
| SCHEMBL31354560 | 0.89 | CETP (0.42) | CETPCSNK1ECTRCSIGMAR1 | |
| SCHEMBL28998085 | 0.88 | CETP (0.45) | CETPCSNK1ECNR2CTRCMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010476-A2 | C-NITROSO-DERIVED NITROXYL DONORS | Wake Forest University Health Sciences (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007120839-A2 | C-NITROSO-DERIVED NITROXYL DONORS | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2007-10-25 | — | — | WO | disclosed |