Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.54 |
| ▸ | TLR2 | O60603 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | EPOR | P19235 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27900292 | 0.83 | TLR4 (0.64) | TLR4TLR2LTA4HTSHRMAOB | |
| SCHEMBL11482497 | 0.81 | MAOB (0.61) | TLR4TLR2LTA4HTSHRMAOB | |
| SCHEMBL3276887 | 0.81 | TLR4 (0.53) | TLR4TLR2LTA4HTSHRMAOB | |
| SCHEMBL29484309 | 0.81 | MAOB (0.61) | TLR4TLR2LTA4HTSHRMAOB | |
| SCHEMBL98478 | 0.81 | MAOB (0.61) | TLR4TLR2LTA4HTSHRMAOB | |
| SCHEMBL11095883 | 0.81 | TLR4 (0.53) | TLR4TLR2LTA4HTSHRMAOB | |
| SCHEMBL11124615 | 0.81 | TLR4 (0.53) | TLR4TLR2LTA4HTSHRMAOB | |
| SCHEMBL11245091 | 0.81 | TLR4 (0.53) | TLR4TLR2LTA4HTSHRMAOB | |
| SCHEMBL1218847 | 0.81 | TLR4 (0.53) | TLR4TLR2LTA4HTSHRMAOB | |
| SCHEMBL34465491 | 0.81 | TLR4 (0.53) | TLR4TLR2LTA4HTSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903377-B | Liquid-applied waterproofing membrane for roofs comprising long-chain aldimines | SIKA技术股份公司 | 2019-07-05 | — | — | CN | disclosed |
| US-7625993-B2 | Polyaldimines | SIKA TECHNOLOGY AG (CH) | 2009-12-01 | — | — | US | disclosed |
| US-20080114146-A1 | Polyurethane composition containing polyaldimine | SIKA TECHNOLOGY AG (CH) | 2008-05-15 | — | — | US | disclosed |
| EP-1527115-B1 | POLYURETHANE COMPOSITIONS CONTAINING POLYALDIMINE | SIKA TECHNOLOGY AG (CH) | 2008-04-23 | — | — | EP | disclosed |
| EP-1527044-B1 | POLYALDIMINES | SIKA TECHNOLOGY AG (CH) | 2007-11-14 | — | — | EP | disclosed |
| CN-1315788-C | Polyaldimines | SIKA TECHNOLOGY AG (CH) | 2007-05-16 | — | — | CN | disclosed |
| CN-1284812-C | Polyurethane compositions containing polyaldimine | SIKA TECHNOLOGY AG (CH) | 2006-11-15 | — | — | CN | disclosed |
| US-20060149025-A1 | Polyaldimines | SIKA TECHNOLOGY AG (CH) | 2006-07-06 | — | — | US | disclosed |
| US-20060122352-A1 | Polyurethane composition containing polyaldimine | SIKA TECHNOLOGY AG (CH) | 2006-06-08 | — | — | US | disclosed |
| CN-1678653-A | Polyurethane compositions containing polyaldimine | SIKA TECHNOLOGY AG (CH) | 2005-10-05 | — | — | CN | disclosed |
| EP-1384709-A1 | Polyaldimines | Sika Technology AG (CH) | 2004-01-28 | — | — | EP | disclosed |
| EP-1384735-A1 | Polyaldimine containing polyurethane composition | Sika Technology AG (CH) | 2004-01-28 | — | — | EP | disclosed |
| EP-0006180-B1 | 3-PHENOXYBENZYLIDENE AMINES AND 3-BENZYLBENZYLIDENE AMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE TO PREPARE THE CORRESPONDING ALDEHYDES | CIBA-GEIGY AG (CH) | 1981-02-11 | — | — | EP | disclosed |
| EP-0006180-B1 | 3-PHENOXYBENZYLIDENE AMINES AND 3-BENZYLBENZYLIDENE AMINES, PROCESS FOR THEIR PREPARATION AND THEIR USE TO PREPARE THE CORRESPONDING ALDEHYDES | CIBA-GEIGY AG (CH) | 1981-02-11 | — | — | EP | disclosed |
| US-4231962-A | 3-Phenoxybenzylideneamines and 3-benzylbenzylideneamines | CIBA-GEIGY CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4231962-A | 3-Phenoxybenzylideneamines and 3-benzylbenzylideneamines | CIBA-GEIGY CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4231962-A | 3-Phenoxybenzylideneamines and 3-benzylbenzylideneamines | CIBA-GEIGY CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| EP-0006180-A1 | 3-Phenoxybenzylidene amines and 3-benzylbenzylidene amines, process for their preparation and their use to prepare the corresponding aldehydes | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |
| EP-0006180-A1 | 3-Phenoxybenzylidene amines and 3-benzylbenzylidene amines, process for their preparation and their use to prepare the corresponding aldehydes | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |
| EP-0006180-A1 | 3-Phenoxybenzylidene amines and 3-benzylbenzylidene amines, process for their preparation and their use to prepare the corresponding aldehydes | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |